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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCHAP00000010458DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae). (663 aa)    
Predicted Functional Partners:
ENSCHAP00000055259
Protein kinase, DNA-activated, catalytic subunit.
    
 0.998
xrcc6
X-ray repair cross complementing 6.
   
 0.996
ENSCHAP00000058293
X-ray repair complementing defective repair in Chinese hamster cells 5.
    
 0.996
lig4
DNA ligase 4.
   
 0.983
ENSCHAP00000002754
Nonhomologous end-joining factor 1.
   
 
 0.963
ENSCHAP00000028521
Cleavage and polyadenylation specific factor 1.
   
 0.956
ENSCHAP00000019339
FA complementation group D2.
   
 0.953
ENSCHAP00000043674
mutS homolog 6 (E. coli).
  
 0.953
xrcc1
X-ray repair cross complementing 1.
     
 0.951
ENSCHAP00000022226
Symplekin.
   
 0.949
Your Current Organism:
Clupea harengus
NCBI taxonomy Id: 7950
Other names: Atlantic herring, C. harengus, Clupea harengus harengus
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