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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCHAP00000010710Polymerase (DNA directed), alpha 1. (1470 aa)    
Predicted Functional Partners:
ENSCHAP00000013600
DNA primase subunit 2.
   
 0.999
prim1
DNA primase subunit 1.
   
 0.999
pola2
DNA polymerase alpha 2, accessory subunit.
   
 0.999
ENSCHAP00000050843
annotation not available
   
 0.999
ENSCHAP00000055365
WD repeat and HMG-box DNA binding protein 1.
   
 
 0.999
ENSCHAP00000031246
Minichromosome maintenance 9 homologous recombination repair factor.
   
 0.998
ENSCHAP00000050893
Polymerase (DNA directed), epsilon 2.
   
 0.998
ENSCHAP00000023162
Minichromosome maintenance complex component 4.
   
 0.997
pcna
Proliferating cell nuclear antigen.
  
 0.996
ENSCHAP00000010628
Polymerase (DNA directed), delta 1, catalytic subunit.
   
0.995
Your Current Organism:
Clupea harengus
NCBI taxonomy Id: 7950
Other names: Atlantic herring, C. harengus, Clupea harengus harengus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.