STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCHAP00000010851MDM2 proto-oncogene. (509 aa)    
Predicted Functional Partners:
ENSCHAP00000003889
MDM4 regulator of p53.
    
0.999
ENSCHAP00000062650
Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4).
   
 0.995
rpl11
Ribosomal protein L11.
    
 
 0.994
ENSCHAP00000039408
Tumor protein p53.
   
 0.993
usp7
Ubiquitin specific peptidase 7.
    
 0.992
rb1
RB transcriptional corepressor 1.
    
 0.991
ENSCHAP00000042143
annotation not available
   
 0.990
ENSCHAP00000039357
Tumor protein p53.
   
 0.985
rps27a
Ribosomal protein S27a.
    
 0.983
ENSCHAP00000030291
Ubiquitin B.
    
 0.979
Your Current Organism:
Clupea harengus
NCBI taxonomy Id: 7950
Other names: Atlantic herring, C. harengus, Clupea harengus harengus
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.