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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
edrf1Erythroid differentiation regulatory factor 1. (1215 aa)    
Predicted Functional Partners:
ENSCHAP00000041841
PPFIA binding protein 1b.
      
 0.538
hikeshi
Heat shock protein nuclear import factor hikeshi.
      
 0.531
ENSCHAP00000041193
annotation not available
      
 0.520
hspbp1
HSPA (Hsp70) binding protein 1.
    
 
 0.480
ENSCHAP00000053289
Tetratricopeptide repeat domain 4.
    
   0.477
ENSCHAP00000020789
Phospholipid phosphatase 6.
      
 0.445
kcnk5
Potassium two pore domain channel subfamily K member 5.
      
 0.426
pacc1
Proton activated chloride channel 1.
      
 0.418
pik3cd
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta.
      
 0.416
LOC105903135
Cysteine and histidine-rich domain-containing protein 1-like.
    
   0.412
Your Current Organism:
Clupea harengus
NCBI taxonomy Id: 7950
Other names: Atlantic herring, C. harengus, Clupea harengus harengus
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