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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCHAP00000011398annotation not available (349 aa)    
Predicted Functional Partners:
fgf8
Fibroblast growth factor 8.
    
 0.887
fgf23
Fibroblast growth factor 23.
    
 0.858
ENSCHAP00000015628
annotation not available
   
 0.841
LOC105892101
Growth factor receptor-bound protein 2.
    
 0.830
ENSCHAP00000018203
Polo-like kinase 4 (Drosophila).
   
 0.828
ENSCHAP00000059854
Gdnf family receptor alpha 1b.
    
 0.825
ENSCHAP00000036391
GDNF family receptor alpha like.
    
 0.823
ENSCHAP00000002770
Fibroblast growth factor 18b.
    
 0.802
ENSCHAP00000003526
Fibroblast growth factor 3.
    
 0.794
fgf4
Fibroblast growth factor 4.
    
 0.793
Your Current Organism:
Clupea harengus
NCBI taxonomy Id: 7950
Other names: Atlantic herring, C. harengus, Clupea harengus harengus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.