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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCHAP00000011414Transcription factor Dp-1, a. (411 aa)    
Predicted Functional Partners:
ENSCHAP00000052975
Retinoblastoma-like 1 (p107).
   
 0.992
rb1
RB transcriptional corepressor 1.
   
 0.987
ENSCHAP00000053582
annotation not available
  
 0.987
ENSCHAP00000050007
E2F transcription factor 5.
  
 0.974
ENSCHAP00000000707
Si:ch211-160f23.5.
   
 0.966
ENSCHAP00000019980
annotation not available
  
 0.964
ENSCHAP00000048310
E2F transcription factor 3.
   
 0.956
E2F4
E2F transcription factor 4.
   
 0.952
ENSCHAP00000035657
annotation not available
   
 0.952
ENSCHAP00000050019
E2F transcription factor 5.
   
 0.948
Your Current Organism:
Clupea harengus
NCBI taxonomy Id: 7950
Other names: Atlantic herring, C. harengus, Clupea harengus harengus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.