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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCHAP00000011804Signal peptidase complex subunit 3. (181 aa)    
Predicted Functional Partners:
ENSCHAP00000043413
Signal peptidase complex subunit 2.
   
 0.999
spcs1
Signal peptidase complex subunit 1.
   
 0.998
sec11a
SEC11 homolog A, signal peptidase complex subunit.
   
 0.996
ENSCHAP00000049223
annotation not available
   
 0.992
immp1l
Inner mitochondrial membrane peptidase subunit 1.
   
 0.932
itfg2
Integrin alpha FG-GAP repeat containing 2.
   
 0.932
ENSCHAP00000027467
Integrin alpha FG-GAP repeat containing 2.
   
 0.932
ENSCHAP00000046449
X-ray repair complementing defective repair in Chinese hamster cells 4.
   
 0.932
ENSCHAP00000001108
ALG2 alpha-1,3/1,6-mannosyltransferase.
   
 
  0.864
ENSCHAP00000044723
annotation not available
   
   0.743
Your Current Organism:
Clupea harengus
NCBI taxonomy Id: 7950
Other names: Atlantic herring, C. harengus, Clupea harengus harengus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.