STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCHAP00000019696ADAM metallopeptidase domain 17b. (843 aa)    
Predicted Functional Partners:
TIMP3
TIMP metallopeptidase inhibitor 3.
    
 0.921
ENSCHAP00000047167
Notch receptor 3.
    
 0.875
ENSCHAP00000054630
Notch receptor 2.
    
 0.871
notch1
Notch receptor 1.
    
 0.866
ENSCHAP00000062382
annotation not available
    
 0.866
LOC105897267
Disintegrin and metalloproteinase domain-containing protein 17-like.
  
  
 
0.852
ENSCHAP00000035186
TIMP metallopeptidase inhibitor 2a.
    
 0.770
LOC105892433
Disintegrin and metalloproteinase domain-containing protein 10-like.
     
0.750
ENSCHAP00000033114
ADAM metallopeptidase domain 10a.
     
0.750
ENSCHAP00000028579
annotation not available
     
 0.678
Your Current Organism:
Clupea harengus
NCBI taxonomy Id: 7950
Other names: Atlantic herring, C. harengus, Clupea harengus harengus
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.