STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCHAP00000020134DNA topoisomerase II beta. (1445 aa)    
Predicted Functional Partners:
ENSCHAP00000046682
Structural maintenance of chromosomes 2.
   
 
 0.948
ENSCHAP00000050616
SPO11 initiator of meiotic double stranded breaks.
    
 0.923
smc4
Structural maintenance of chromosomes 4.
   
 
 0.906
ube2c
Ubiquitin conjugating enzyme E2 C.
   
 0.892
ENSCHAP00000016921
Zgc:173742.
   
 
 0.891
ENSCHAP00000050971
DNA topoisomerase I.
   
 
 0.891
ENSCHAP00000015966
non-SMC condensin I complex, subunit H.
   
 
 0.889
LOC105890282
DNA topoisomerase I, mitochondrial-like.
   
 
 0.881
pcna
Proliferating cell nuclear antigen.
  
 
 0.872
ENSCHAP00000020403
Discs, large (Drosophila) homolog-associated protein 5.
   
  
 0.870
Your Current Organism:
Clupea harengus
NCBI taxonomy Id: 7950
Other names: Atlantic herring, C. harengus, Clupea harengus harengus
Server load: low (22%) [HD]