STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
optnOptineurin. (521 aa)    
Predicted Functional Partners:
ikbkb
Inhibitor of nuclear factor kappa B kinase subunit beta.
    
 0.950
ENSCHAP00000020479
annotation not available
    
 0.950
ENSCHAP00000028066
Component of inhibitor of nuclear factor kappa B kinase complex.
    
 0.950
ENSCHAP00000029505
TANK-binding kinase 1.
    
 0.922
ENSCHAP00000047220
Inhibitor of nuclear factor kappa B kinase subunit epsilon.
    
 0.922
ENSCHAP00000048013
Mitogen-activated protein kinase kinase kinase 7.
    
 0.897
ENSCHAP00000015917
Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.
    
 0.883
ENSCHAP00000040398
Interleukin-1 receptor-associated kinase 4.
    
 0.873
LOC105895017
Gamma-aminobutyric acid receptor-associated protein-like 1.
    
  0.867
ENSCHAP00000001336
TGF-beta activated kinase 1 (MAP3K7) binding protein 3.
     
 0.866
Your Current Organism:
Clupea harengus
NCBI taxonomy Id: 7950
Other names: Atlantic herring, C. harengus, Clupea harengus harengus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.