STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pik3r2Phosphoinositide-3-kinase regulatory subunit 2. (755 aa)    
Predicted Functional Partners:
gab1
GRB2 associated binding protein 1.
    
 0.917
LOC105892101
Growth factor receptor-bound protein 2.
    
0.904
irs1
Insulin receptor substrate 1.
    
 0.904
ENSCHAP00000039433
Inositol polyphosphate phosphatase-like 1b.
    
 0.903
pik3cd
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta.
    
 0.890
ENSCHAP00000025932
Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta.
    
 0.890
ENSCHAP00000022623
Kinase insert domain receptor (a type III receptor tyrosine kinase).
    
 0.887
ENSCHAP00000016391
Macrophage stimulating 1 receptor b.
    
 0.886
ENSCHAP00000041906
Macrophage stimulating 1 receptor a.
    
 0.886
ENSCHAP00000053649
MET proto-oncogene, receptor tyrosine kinase.
    
 0.886
Your Current Organism:
Clupea harengus
NCBI taxonomy Id: 7950
Other names: Atlantic herring, C. harengus, Clupea harengus harengus
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.