STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCHAP00000051971Mitogen-activated protein kinase kinase 1. (295 aa)    
Predicted Functional Partners:
braf
B-Raf proto-oncogene, serine/threonine kinase.
   
0.948
araf
A-Raf proto-oncogene, serine/threonine kinase.
   
 0.944
ENSCHAP00000026943
Mitogen-activated protein kinase 3.
   
0.940
mapk1
Mitogen-activated protein kinase 1.
   
0.937
map3k4
Mitogen-activated protein kinase kinase kinase 4.
   
0.922
lamtor3
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3.
    
 0.914
ksr1
Kinase suppressor of ras 1.
   
 0.906
ENSCHAP00000013496
Kinase suppressor of ras 2.
   
 0.906
ENSCHAP00000024276
Mitogen-activated protein kinase kinase kinase 8.
  
 
0.903
raf1
Raf-1 proto-oncogene, serine/threonine kinase.
   
0.903
Your Current Organism:
Clupea harengus
NCBI taxonomy Id: 7950
Other names: Atlantic herring, C. harengus, Clupea harengus harengus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.