STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCHAP00000052633Dihydrofolate reductase. (190 aa)    
Predicted Functional Partners:
ENSCHAP00000009497
Thymidylate synthetase.
 
 
 0.994
gart
annotation not available
  
 
 0.948
shmt2
Serine hydroxymethyltransferase 2.
  
 
 0.927
ENSCHAP00000012912
Folylpolyglutamate synthase.
    
 0.924
mtfmt
Mitochondrial methionyl-tRNA formyltransferase.
  
 
 0.918
mtr
5-methyltetrahydrofolate-homocysteine methyltransferase.
    
 0.913
ENSCHAP00000054107
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.
    
 0.913
aldh1l2
Aldehyde dehydrogenase 1 family member L2.
  
 
 0.907
LOC105901876
Cytosolic 10-formyltetrahydrofolate dehydrogenase-like.
  
 
 0.905
LOC105908326
C-1-tetrahydrofolate synthase, cytoplasmic-like.
  
 
 0.902
Your Current Organism:
Clupea harengus
NCBI taxonomy Id: 7950
Other names: Atlantic herring, C. harengus, Clupea harengus harengus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.