STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCHAP00000060368Vav 2 guanine nucleotide exchange factor. (876 aa)    
Predicted Functional Partners:
LOC105892187
Ras-related C3 botulinum toxin substrate 2.
   
 0.913
rac3
Rac family small GTPase 3.
   
 0.905
LOC105892101
Growth factor receptor-bound protein 2.
    
0.887
ENSCHAP00000057288
Phosphoinositide-3-kinase, regulatory subunit 1 (alpha).
    
 
0.856
ENSCHAP00000042865
Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).
    
  0.838
pik3ca
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha.
   
 
  0.822
pik3cd
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta.
   
 
  0.822
ENSCHAP00000025932
Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta.
   
 
  0.822
ENSCHAP00000033549
Zeta chain of T cell receptor associated protein kinase 70.
   
 0.797
ENSCHAP00000042878
Spleen tyrosine kinase.
   
 0.797
Your Current Organism:
Clupea harengus
NCBI taxonomy Id: 7950
Other names: Atlantic herring, C. harengus, Clupea harengus harengus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.