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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
fabH3-oxoacyl-(acyl-carrier-protein) synthase 3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (332 aa)    
Predicted Functional Partners:
AEH23354.1
KEGG: dak:DaAHT2_0461 acetyl-CoA carboxylase; PFAM: Acetyl-CoA carboxylase, alpha subunit, conserved region.
 
 
 0.999
AEH22776.1
TIGRFAM: Malonyl CoA-acyl carrier protein transacylase; KEGG: dal:Dalk_3440 malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase.
 
 
 0.997
AEH22132.1
3-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 
 0.990
AEH23380.1
KEGG: dth:DICTH_0796 3-oxoacyl-[acyl-carrier-protein] synthase II; PFAM: Beta-ketoacyl synthase, C-terminal; Beta-ketoacyl synthase, N-terminal; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 
 0.990
plsX
Phosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
  
  
 0.985
fabZ
(3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
 
  
 0.977
AEH23675.1
3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
 0.959
AEH22814.1
Pyruvate carboxylase; KEGG: rca:Rcas_2955 carbamoyl-phosphate synthase L chain ATP-binding; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthase, large subunit, N-terminal; Biotin carboxylase, C-terminal.
 
 
 0.939
AEH23355.1
KEGG: dak:DaAHT2_0462 hypothetical protein.
  
  
 0.906
rpmF
TIGRFAM: Ribosomal protein L32p; HAMAP: Ribosomal protein L32p; KEGG: geo:Geob_2610 50S ribosomal protein L32; PFAM: Ribosomal protein L32p; Belongs to the bacterial ribosomal protein bL32 family.
  
  
 0.828
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
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