Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH22219.1CoA-binding domain protein; PFAM: CoA-binding; KEGG: tvo:TVN0743 CoA-binding protein. (148 aa)    
Predicted Functional Partners:
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
       0.792
pgk
HAMAP: Phosphoglycerate kinase; KEGG: ddf:DEFDS_1892 phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
     
 0.784
AEH22218.1
PFAM: Prokaryotic chromosome segregation/condensation protein ScpA.
       0.779
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
       0.732
AEH22223.1
PFAM: Septum formation initiator.
       0.732
AEH22224.1
Hypothetical protein.
       0.732
AEH22225.1
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
       0.732
AEH22624.1
Ferric uptake regulator, Fur family; PFAM: Ferric-uptake regulator; KEGG: pmx:PERMA_1658 transcriptional regulator; Belongs to the Fur family.
  
    0.576
AEH23684.1
Ferric uptake regulator, Fur family; PFAM: Ferric-uptake regulator; KEGG: pth:PTH_0045 Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family.
  
    0.576
AEH22227.1
Hypothetical protein; KEGG: pmo:Pmob_0084 exonuclease SbcC.
       0.569
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
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