| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEH22218.1 | AEH22219.1 | TOPB45_0102 | TOPB45_0103 | PFAM: Prokaryotic chromosome segregation/condensation protein ScpA. | CoA-binding domain protein; PFAM: CoA-binding; KEGG: tvo:TVN0743 CoA-binding protein. | 0.783 |
| AEH22218.1 | AEH22223.1 | TOPB45_0102 | TOPB45_0107 | PFAM: Prokaryotic chromosome segregation/condensation protein ScpA. | PFAM: Septum formation initiator. | 0.732 |
| AEH22218.1 | AEH22224.1 | TOPB45_0102 | TOPB45_0108 | PFAM: Prokaryotic chromosome segregation/condensation protein ScpA. | Hypothetical protein. | 0.732 |
| AEH22218.1 | AEH22225.1 | TOPB45_0102 | TOPB45_0109 | PFAM: Prokaryotic chromosome segregation/condensation protein ScpA. | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | 0.732 |
| AEH22218.1 | mobA | TOPB45_0102 | TOPB45_0112 | PFAM: Prokaryotic chromosome segregation/condensation protein ScpA. | Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. | 0.509 |
| AEH22218.1 | pgk | TOPB45_0102 | TOPB45_0105 | PFAM: Prokaryotic chromosome segregation/condensation protein ScpA. | HAMAP: Phosphoglycerate kinase; KEGG: ddf:DEFDS_1892 phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | 0.778 |
| AEH22218.1 | ribH | TOPB45_0102 | TOPB45_0106 | PFAM: Prokaryotic chromosome segregation/condensation protein ScpA. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.735 |
| AEH22218.1 | smpB | TOPB45_0102 | TOPB45_0110 | PFAM: Prokaryotic chromosome segregation/condensation protein ScpA. | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | 0.509 |
| AEH22218.1 | tpiA | TOPB45_0102 | TOPB45_0104 | PFAM: Prokaryotic chromosome segregation/condensation protein ScpA. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.780 |
| AEH22219.1 | AEH22218.1 | TOPB45_0103 | TOPB45_0102 | CoA-binding domain protein; PFAM: CoA-binding; KEGG: tvo:TVN0743 CoA-binding protein. | PFAM: Prokaryotic chromosome segregation/condensation protein ScpA. | 0.783 |
| AEH22219.1 | AEH22223.1 | TOPB45_0103 | TOPB45_0107 | CoA-binding domain protein; PFAM: CoA-binding; KEGG: tvo:TVN0743 CoA-binding protein. | PFAM: Septum formation initiator. | 0.732 |
| AEH22219.1 | AEH22224.1 | TOPB45_0103 | TOPB45_0108 | CoA-binding domain protein; PFAM: CoA-binding; KEGG: tvo:TVN0743 CoA-binding protein. | Hypothetical protein. | 0.732 |
| AEH22219.1 | AEH22225.1 | TOPB45_0103 | TOPB45_0109 | CoA-binding domain protein; PFAM: CoA-binding; KEGG: tvo:TVN0743 CoA-binding protein. | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | 0.732 |
| AEH22219.1 | mobA | TOPB45_0103 | TOPB45_0112 | CoA-binding domain protein; PFAM: CoA-binding; KEGG: tvo:TVN0743 CoA-binding protein. | Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. | 0.509 |
| AEH22219.1 | pgk | TOPB45_0103 | TOPB45_0105 | CoA-binding domain protein; PFAM: CoA-binding; KEGG: tvo:TVN0743 CoA-binding protein. | HAMAP: Phosphoglycerate kinase; KEGG: ddf:DEFDS_1892 phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | 0.778 |
| AEH22219.1 | ribH | TOPB45_0103 | TOPB45_0106 | CoA-binding domain protein; PFAM: CoA-binding; KEGG: tvo:TVN0743 CoA-binding protein. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.735 |
| AEH22219.1 | smpB | TOPB45_0103 | TOPB45_0110 | CoA-binding domain protein; PFAM: CoA-binding; KEGG: tvo:TVN0743 CoA-binding protein. | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | 0.509 |
| AEH22219.1 | tpiA | TOPB45_0103 | TOPB45_0104 | CoA-binding domain protein; PFAM: CoA-binding; KEGG: tvo:TVN0743 CoA-binding protein. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.804 |
| AEH22223.1 | AEH22218.1 | TOPB45_0107 | TOPB45_0102 | PFAM: Septum formation initiator. | PFAM: Prokaryotic chromosome segregation/condensation protein ScpA. | 0.732 |
| AEH22223.1 | AEH22219.1 | TOPB45_0107 | TOPB45_0103 | PFAM: Septum formation initiator. | CoA-binding domain protein; PFAM: CoA-binding; KEGG: tvo:TVN0743 CoA-binding protein. | 0.732 |