Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mqnDHypothetical protein; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. (275 aa)    
Predicted Functional Partners:
AEH22232.1
PFAM: Nucleoside phosphorylase; KEGG: ppd:Ppro_3274 purine phosphorylases family protein 1.
 
   
 0.959
mqnA
Protein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).
 
   
 0.854
AEH22234.1
PFAM: MotA/TolQ/ExbB proton channel; KEGG: tye:THEYE_A0959 TolQ protein.
       0.815
mqnC
Menaquinone biosynthesis protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).
 
   
 0.790
AEH22608.1
TIGRFAM: FO synthase, subunit 2; PFAM: Radical SAM; KEGG: tam:Theam_0970 radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB.
 
   
 0.790
AEH22231.1
Hypothetical protein.
       0.779
AEH22336.1
KEGG: aae:aq_052 4-hydroxybenzoate octaprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase related; PFAM: UbiA prenyltransferase; Belongs to the UbiA prenyltransferase family.
  
     0.764
AEH22230.1
PFAM: Protein of unknown function DUF72; KEGG: tye:THEYE_A1271 DUF72.
       0.560
AEH22235.1
Thioredoxin; KEGG: dbr:Deba_1136 thioredoxin; TIGRFAM: Thioredoxin; PFAM: Thioredoxin domain; Belongs to the thioredoxin family.
       0.554
AEH22236.1
TIGRFAM: Outer membrane assembly lipoprotein YfiO; KEGG: dak:DaAHT2_1639 outer membrane assembly lipoprotein YfiO.
       0.540
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
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