Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH22235.1Thioredoxin; KEGG: dbr:Deba_1136 thioredoxin; TIGRFAM: Thioredoxin; PFAM: Thioredoxin domain; Belongs to the thioredoxin family. (108 aa)    
Predicted Functional Partners:
AEH23688.1
TIGRFAM: Thioredoxin reductase; KEGG: dpr:Despr_2956 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
 
 0.961
AEH23695.1
Thioredoxin-disulfide reductase; KEGG: dak:DaAHT2_0308 FAD-dependent pyridine nucleotide-disulfide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
 
 0.895
groL
60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.885
AEH23080.1
Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
  
 
 0.840
AEH22236.1
TIGRFAM: Outer membrane assembly lipoprotein YfiO; KEGG: dak:DaAHT2_1639 outer membrane assembly lipoprotein YfiO.
  
  
 0.789
AEH22496.1
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: tye:THEYE_A0446 oxidoreductase.
  
 
 0.789
AEH22658.1
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
 
 0.713
AEH23336.1
KEGG: hth:HTH_0871 ferredoxin-dependent glutamate synthase; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal.
    
 
 0.636
fusA
Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]
    
 
 0.627
AEH23522.1
Small GTP-binding protein; KEGG: ddf:DEFDS_1534 translation elongation factor G; TIGRFAM: Small GTP-binding protein; PFAM: Translation elongation factor EFG/EF2, domain IV; Protein synthesis factor, GTP-binding; Translation elongation factor EFG/EF2, C-terminal.
    
 
 0.627
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
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