STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nfiEndonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. (219 aa)    
Predicted Functional Partners:
AEH22259.1
Hypothetical protein; KEGG: mel:Metbo_0698 type 11 methyltransferase.
       0.569
AEH22261.1
Site-specific DNA-methyltransferase (adenine-specific); KEGG: mja:MJECL42 type I restriction system protein M; PFAM: DNA methylase, adenine-specific.
   
   0.564
AEH22262.1
KEGG: hpa:HPAG1_1365 hypothetical protein.
       0.526
AEH22263.1
Domain of unknown function DUF1863; PFAM: MTH538 TIR-like domain; KEGG: mms:mma_2730 hypothetical protein.
       0.526
AEH22264.1
Restriction modification system DNA specificity domain protein; PFAM: Restriction endonuclease, type I, S subunit, EcoBI; KEGG: mja:MJECL41 type I restriction enzyme subunit S.
       0.526
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
  
 0.413
AEH22265.1
DNA polymerase beta domain protein region; PFAM: Nucleotidyltransferase; KEGG: mac:MA0099 hypothetical protein.
       0.409
AEH22266.1
KEGG: hya:HY04AAS1_1590 nucleotidyltransferase substrate binding protein, HI0074 family; TIGRFAM: Nucleotidyltransferase substrate binding protein, HI0074; PFAM: Nucleotidyltransferase substrate binding protein, HI0074.
       0.409
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.