STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH22331.1TIGRFAM: HDIG; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; KEGG: tye:THEYE_A1310 HD domain protein; SMART: Metal-dependent phosphohydrolase, HD region. (183 aa)    
Predicted Functional Partners:
mutL
DNA mismatch repair protein mutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
       0.779
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
       0.778
AEH22329.1
PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, C-terminal; KEGG: sat:SYN_00938 phosphomannomutase.
       0.773
AEH22330.1
PFAM: Protein of unknown function DUF721.
       0.773
miaA
tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
       0.763
AEH22336.1
KEGG: aae:aq_052 4-hydroxybenzoate octaprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase related; PFAM: UbiA prenyltransferase; Belongs to the UbiA prenyltransferase family.
       0.752
AEH22335.1
KEGG: fma:FMG_0655 hypothetical protein; TIGRFAM: Conserved hypothetical protein CHP00255; PFAM: YicC-like, N-terminal; Domain of unknown function DUF1732.
       0.751
AEH22337.1
PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: fjo:Fjoh_0202 cobyrinic acid a,c-diamide synthase.
       0.748
AEH22327.1
Hypothetical protein.
       0.526
AEH22328.1
Hypothetical protein.
       0.526
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
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