STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (308 aa)    
Predicted Functional Partners:
AEH22348.1
TIGRFAM: Fe-S type hydro-lyases tartrate/fumarate alpha region; KEGG: dte:Dester_0737 hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; PFAM: Fe-S type hydro-lyases tartrate/fumarate alpha region.
  
 
 0.969
AEH23702.1
Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; TIGRFAM: Fe-S type hydro-lyases tartrate/fumarate beta region; KEGG: saf:SULAZ_0637 fumarate hydratase, class I; PFAM: Fe-S type hydro-lyases tartrate/fumarate beta region.
  
 
 0.969
AEH22815.1
Pyruvate carboxylase; KEGG: rca:Rcas_2954 biotin/lipoyl attachment domain-containing protein; PFAM: Biotin/lipoyl attachment; Conserved carboxylase region; Pyruvate carboxyltransferase.
   
 0.938
AEH23514.1
TIGRFAM: Isocitrate dehydrogenase NADP-dependent, prokaryotic; KEGG: sfu:Sfum_3896 isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate/isopropylmalate dehydrogenase.
  
 
 0.936
AEH22783.1
KEGG: mgm:Mmc1_0698 L-aspartate aminotransferase; PFAM: Aminotransferase, class I/II.
  
 0.914
AEH23303.1
Aspartate transaminase; KEGG: dpr:Despr_1050 class I/II aminotransferase; PFAM: Aminotransferase, class I/II.
  
 0.914
AEH23640.1
Putative cache sensor protein; PFAM: Pyruvate carboxyltransferase; Cache; KEGG: sfu:Sfum_3301 pyruvate carboxyltransferase.
   
 0.912
AEH23660.1
PFAM: Phosphoenolpyruvate carboxylase_subgroup; TIGRFAM: Phosphoenolpyruvate carboxylase_subgroup; HAMAP: Phosphoenolpyruvate carboxylase_subgroup; KEGG: dau:Daud_0773 phosphoenolpyruvate carboxylase.
     
 0.912
AEH23336.1
KEGG: hth:HTH_0871 ferredoxin-dependent glutamate synthase; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal.
  
 
 0.897
AEH22307.1
KEGG: tam:Theam_1017 adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; PFAM: Fumarate lyase; Adenylosuccinate lyase, C-terminal.
   
 0.837
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
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