Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH22337.1PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: fjo:Fjoh_0202 cobyrinic acid a,c-diamide synthase. (261 aa)    
Predicted Functional Partners:
AEH22700.1
TIGRFAM: ParB-like partition protein; PFAM: ParB-like nuclease; KorB; KEGG: tye:THEYE_A1991 stage 0 sporulation protein J; SMART: ParB-like nuclease; Belongs to the ParB family.
 
 
 0.925
AEH22335.1
KEGG: fma:FMG_0655 hypothetical protein; TIGRFAM: Conserved hypothetical protein CHP00255; PFAM: YicC-like, N-terminal; Domain of unknown function DUF1732.
       0.783
AEH22336.1
KEGG: aae:aq_052 4-hydroxybenzoate octaprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase related; PFAM: UbiA prenyltransferase; Belongs to the UbiA prenyltransferase family.
       0.779
miaA
tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
  
    0.772
mutL
DNA mismatch repair protein mutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
  
    0.756
AEH22329.1
PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, C-terminal; KEGG: sat:SYN_00938 phosphomannomutase.
       0.751
AEH22330.1
PFAM: Protein of unknown function DUF721.
       0.746
AEH22331.1
TIGRFAM: HDIG; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; KEGG: tye:THEYE_A1310 HD domain protein; SMART: Metal-dependent phosphohydrolase, HD region.
       0.746
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
       0.746
AEH23046.1
KEGG: aae:aq_324 hypothetical protein; PFAM: ParB-like nuclease; SMART: ParB-like nuclease.
  
 
 0.683
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
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