Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH22378.1ErfK/YbiS/YcfS/YnhG family protein; PFAM: YkuD domain; KEGG: noc:Noc_0717 hypothetical protein. (244 aa)    
Predicted Functional Partners:
AEH22321.1
PFAM: YkuD domain; KEGG: nwa:Nwat_1413 ErfK/YbiS/YcfS/YnhG family protein.
 
  
 0.780
cysS
TIGRFAM: Cysteine synthase K/M; Cysteinyl-tRNA synthetase, class Ia; KEGG: dpr:Despr_3183 cysteine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; Cysteinyl-tRNA synthetase, class Ia, N-terminal; Belongs to the class-I aminoacyl-tRNA synthetase family.
       0.616
AEH22381.1
PFAM: Protein of unknown function DUF6, transmembrane; KEGG: sat:SYN_00035 DMT family permease.
 
     0.555
AEH22380.1
HhH-GPD family protein; KEGG: dpr:Despr_2593 DNA-3-methyladenine glycosylase III; PFAM: HhH-GPD domain; SMART: HhH-GPD domain.
       0.528
mqnC
Menaquinone biosynthesis protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).
  
    0.470
AEH22382.1
ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; PFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR; KEGG: aps:CFPG_329 cob(I)alamin adenosyltransferase.
       0.459
AEH22384.1
S-adenosylhomocysteine deaminase; KEGG: dpr:Despr_1798 amidohydrolase; PFAM: Amidohydrolase 1.
       0.459
mqnA
Protein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).
       0.459
menG
Ubiquinone/menaquinone biosynthesis methyltransferase ubiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
       0.456
AEH22563.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: Diguanylate cyclase, predicted; PAS; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; KEGG: saf:SULAZ_0401 PAS fold family protein; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; PAS.
     
 0.440
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
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