Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cysSTIGRFAM: Cysteine synthase K/M; Cysteinyl-tRNA synthetase, class Ia; KEGG: dpr:Despr_3183 cysteine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; Cysteinyl-tRNA synthetase, class Ia, N-terminal; Belongs to the class-I aminoacyl-tRNA synthetase family. (778 aa)    
Predicted Functional Partners:
cysS-2
TIGRFAM: Cysteinyl-tRNA synthetase, class Ia; KEGG: tye:THEYE_A1975 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase, class Ia, N-terminal; Cysteinyl-tRNA synthetase, class Ia, DALR; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
0.920
AEH22380.1
HhH-GPD family protein; KEGG: dpr:Despr_2593 DNA-3-methyladenine glycosylase III; PFAM: HhH-GPD domain; SMART: HhH-GPD domain.
       0.818
mqnC
Menaquinone biosynthesis protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).
     
 0.791
AEH22381.1
PFAM: Protein of unknown function DUF6, transmembrane; KEGG: sat:SYN_00035 DMT family permease.
     
 0.754
AEH22615.1
Hypothetical protein.
   
 0.751
serS
Seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
 
 
 0.748
menG
Ubiquinone/menaquinone biosynthesis methyltransferase ubiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
  
  
 0.736
metG
Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
 
 0.712
lysS
PFAM: Aminoacyl-tRNA synthetase, class II (D/K/N); Nucleic acid binding, OB-fold, tRNA/helicase-type; TIGRFAM: Lysyl-tRNA synthetase, class II; HAMAP: Lysyl-tRNA synthetase; KEGG: dvl:Dvul_0888 lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
 
 0.700
AEH22384.1
S-adenosylhomocysteine deaminase; KEGG: dpr:Despr_1798 amidohydrolase; PFAM: Amidohydrolase 1.
       0.693
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
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