Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
AEH22381.1PFAM: Protein of unknown function DUF6, transmembrane; KEGG: sat:SYN_00035 DMT family permease. (294 aa)    
Predicted Functional Partners:
AEH22382.1
ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; PFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR; KEGG: aps:CFPG_329 cob(I)alamin adenosyltransferase.
       0.767
AEH22384.1
S-adenosylhomocysteine deaminase; KEGG: dpr:Despr_1798 amidohydrolase; PFAM: Amidohydrolase 1.
       0.767
mqnC
Menaquinone biosynthesis protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).
       0.762
mqnA
Protein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).
       0.762
menG
Ubiquinone/menaquinone biosynthesis methyltransferase ubiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
       0.762
AEH22380.1
HhH-GPD family protein; KEGG: dpr:Despr_2593 DNA-3-methyladenine glycosylase III; PFAM: HhH-GPD domain; SMART: HhH-GPD domain.
 
    0.761
cysS
TIGRFAM: Cysteine synthase K/M; Cysteinyl-tRNA synthetase, class Ia; KEGG: dpr:Despr_3183 cysteine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; Cysteinyl-tRNA synthetase, class Ia, N-terminal; Belongs to the class-I aminoacyl-tRNA synthetase family.
     
 0.754
AEH22387.1
TIGRFAM: Diguanylate cyclase, predicted; PFAM: Diguanylate cyclase, predicted; KEGG: tcx:Tcr_1143 diguanylate cyclase; SMART: Diguanylate cyclase, predicted.
  
    0.679
AEH22184.1
Hypothetical protein; KEGG: pmx:PERMA_0605 putative peptidase M1, membrane alanine aminopeptidase.
  
     0.617
AEH22378.1
ErfK/YbiS/YcfS/YnhG family protein; PFAM: YkuD domain; KEGG: noc:Noc_0717 hypothetical protein.
 
     0.555
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
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