| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEH22295.1 | menG | TOPB45_0180 | TOPB45_0272 | KEGG: sfu:Sfum_1586 trans-hexaprenyltranstransferase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Ubiquinone/menaquinone biosynthesis methyltransferase ubiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). | 0.668 |
| AEH22380.1 | AEH22381.1 | TOPB45_0266 | TOPB45_0267 | HhH-GPD family protein; KEGG: dpr:Despr_2593 DNA-3-methyladenine glycosylase III; PFAM: HhH-GPD domain; SMART: HhH-GPD domain. | PFAM: Protein of unknown function DUF6, transmembrane; KEGG: sat:SYN_00035 DMT family permease. | 0.761 |
| AEH22380.1 | AEH22382.1 | TOPB45_0266 | TOPB45_0268 | HhH-GPD family protein; KEGG: dpr:Despr_2593 DNA-3-methyladenine glycosylase III; PFAM: HhH-GPD domain; SMART: HhH-GPD domain. | ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; PFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR; KEGG: aps:CFPG_329 cob(I)alamin adenosyltransferase. | 0.672 |
| AEH22380.1 | AEH22384.1 | TOPB45_0266 | TOPB45_0270 | HhH-GPD family protein; KEGG: dpr:Despr_2593 DNA-3-methyladenine glycosylase III; PFAM: HhH-GPD domain; SMART: HhH-GPD domain. | S-adenosylhomocysteine deaminase; KEGG: dpr:Despr_1798 amidohydrolase; PFAM: Amidohydrolase 1. | 0.673 |
| AEH22380.1 | AEH22387.1 | TOPB45_0266 | TOPB45_0273 | HhH-GPD family protein; KEGG: dpr:Despr_2593 DNA-3-methyladenine glycosylase III; PFAM: HhH-GPD domain; SMART: HhH-GPD domain. | TIGRFAM: Diguanylate cyclase, predicted; PFAM: Diguanylate cyclase, predicted; KEGG: tcx:Tcr_1143 diguanylate cyclase; SMART: Diguanylate cyclase, predicted. | 0.601 |
| AEH22380.1 | cysS | TOPB45_0266 | TOPB45_0265 | HhH-GPD family protein; KEGG: dpr:Despr_2593 DNA-3-methyladenine glycosylase III; PFAM: HhH-GPD domain; SMART: HhH-GPD domain. | TIGRFAM: Cysteine synthase K/M; Cysteinyl-tRNA synthetase, class Ia; KEGG: dpr:Despr_3183 cysteine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; Cysteinyl-tRNA synthetase, class Ia, N-terminal; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.818 |
| AEH22380.1 | menG | TOPB45_0266 | TOPB45_0272 | HhH-GPD family protein; KEGG: dpr:Despr_2593 DNA-3-methyladenine glycosylase III; PFAM: HhH-GPD domain; SMART: HhH-GPD domain. | Ubiquinone/menaquinone biosynthesis methyltransferase ubiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). | 0.667 |
| AEH22380.1 | mqnA | TOPB45_0266 | TOPB45_0271 | HhH-GPD family protein; KEGG: dpr:Despr_2593 DNA-3-methyladenine glycosylase III; PFAM: HhH-GPD domain; SMART: HhH-GPD domain. | Protein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.672 |
| AEH22380.1 | mqnC | TOPB45_0266 | TOPB45_0269 | HhH-GPD family protein; KEGG: dpr:Despr_2593 DNA-3-methyladenine glycosylase III; PFAM: HhH-GPD domain; SMART: HhH-GPD domain. | Menaquinone biosynthesis protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.672 |
| AEH22381.1 | AEH22380.1 | TOPB45_0267 | TOPB45_0266 | PFAM: Protein of unknown function DUF6, transmembrane; KEGG: sat:SYN_00035 DMT family permease. | HhH-GPD family protein; KEGG: dpr:Despr_2593 DNA-3-methyladenine glycosylase III; PFAM: HhH-GPD domain; SMART: HhH-GPD domain. | 0.761 |
| AEH22381.1 | AEH22382.1 | TOPB45_0267 | TOPB45_0268 | PFAM: Protein of unknown function DUF6, transmembrane; KEGG: sat:SYN_00035 DMT family permease. | ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; PFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR; KEGG: aps:CFPG_329 cob(I)alamin adenosyltransferase. | 0.767 |
| AEH22381.1 | AEH22384.1 | TOPB45_0267 | TOPB45_0270 | PFAM: Protein of unknown function DUF6, transmembrane; KEGG: sat:SYN_00035 DMT family permease. | S-adenosylhomocysteine deaminase; KEGG: dpr:Despr_1798 amidohydrolase; PFAM: Amidohydrolase 1. | 0.767 |
| AEH22381.1 | AEH22387.1 | TOPB45_0267 | TOPB45_0273 | PFAM: Protein of unknown function DUF6, transmembrane; KEGG: sat:SYN_00035 DMT family permease. | TIGRFAM: Diguanylate cyclase, predicted; PFAM: Diguanylate cyclase, predicted; KEGG: tcx:Tcr_1143 diguanylate cyclase; SMART: Diguanylate cyclase, predicted. | 0.679 |
| AEH22381.1 | cysS | TOPB45_0267 | TOPB45_0265 | PFAM: Protein of unknown function DUF6, transmembrane; KEGG: sat:SYN_00035 DMT family permease. | TIGRFAM: Cysteine synthase K/M; Cysteinyl-tRNA synthetase, class Ia; KEGG: dpr:Despr_3183 cysteine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; Cysteinyl-tRNA synthetase, class Ia, N-terminal; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.754 |
| AEH22381.1 | menG | TOPB45_0267 | TOPB45_0272 | PFAM: Protein of unknown function DUF6, transmembrane; KEGG: sat:SYN_00035 DMT family permease. | Ubiquinone/menaquinone biosynthesis methyltransferase ubiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). | 0.762 |
| AEH22381.1 | mqnA | TOPB45_0267 | TOPB45_0271 | PFAM: Protein of unknown function DUF6, transmembrane; KEGG: sat:SYN_00035 DMT family permease. | Protein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.762 |
| AEH22381.1 | mqnC | TOPB45_0267 | TOPB45_0269 | PFAM: Protein of unknown function DUF6, transmembrane; KEGG: sat:SYN_00035 DMT family permease. | Menaquinone biosynthesis protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.762 |
| AEH22382.1 | AEH22380.1 | TOPB45_0268 | TOPB45_0266 | ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; PFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR; KEGG: aps:CFPG_329 cob(I)alamin adenosyltransferase. | HhH-GPD family protein; KEGG: dpr:Despr_2593 DNA-3-methyladenine glycosylase III; PFAM: HhH-GPD domain; SMART: HhH-GPD domain. | 0.672 |
| AEH22382.1 | AEH22381.1 | TOPB45_0268 | TOPB45_0267 | ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; PFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR; KEGG: aps:CFPG_329 cob(I)alamin adenosyltransferase. | PFAM: Protein of unknown function DUF6, transmembrane; KEGG: sat:SYN_00035 DMT family permease. | 0.767 |
| AEH22382.1 | AEH22384.1 | TOPB45_0268 | TOPB45_0270 | ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; PFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR; KEGG: aps:CFPG_329 cob(I)alamin adenosyltransferase. | S-adenosylhomocysteine deaminase; KEGG: dpr:Despr_1798 amidohydrolase; PFAM: Amidohydrolase 1. | 0.780 |