| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEH22408.1 | AEH22433.1 | TOPB45_0294 | TOPB45_0321 | PFAM: Phosphoglucose isomerase (PGI); KEGG: sfu:Sfum_1952 phosphoglucose isomerase; Belongs to the GPI family. | TIGRFAM: Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; KEGG: dte:Dester_1366 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: Mannose-6-phosphate isomerase, type II, C-terminal; Nucleotidyl transferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.952 |
| AEH22408.1 | AEH22515.1 | TOPB45_0294 | TOPB45_0411 | PFAM: Phosphoglucose isomerase (PGI); KEGG: sfu:Sfum_1952 phosphoglucose isomerase; Belongs to the GPI family. | Glucokinase; KEGG: plu:plu1405 glucokinase; PFAM: Glucokinase; Belongs to the bacterial glucokinase family. | 0.935 |
| AEH22408.1 | AEH23136.1 | TOPB45_0294 | TOPB45_1042 | PFAM: Phosphoglucose isomerase (PGI); KEGG: sfu:Sfum_1952 phosphoglucose isomerase; Belongs to the GPI family. | TIGRFAM: Pyruvate kinase; KEGG: pmx:PERMA_0022 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; Belongs to the pyruvate kinase family. | 0.984 |
| AEH22408.1 | AEH23467.1 | TOPB45_0294 | TOPB45_1386 | PFAM: Phosphoglucose isomerase (PGI); KEGG: sfu:Sfum_1952 phosphoglucose isomerase; Belongs to the GPI family. | KEGG: tpe:Tpen_0757 glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.929 |
| AEH22408.1 | AEH23481.1 | TOPB45_0294 | TOPB45_1400 | PFAM: Phosphoglucose isomerase (PGI); KEGG: sfu:Sfum_1952 phosphoglucose isomerase; Belongs to the GPI family. | 1-deoxy-D-xylulose-5-phosphate synthase; KEGG: sfu:Sfum_1302 transketolase; PFAM: Transketolase, N-terminal; Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal. | 0.983 |
| AEH22408.1 | eno | TOPB45_0294 | TOPB45_0128 | PFAM: Phosphoglucose isomerase (PGI); KEGG: sfu:Sfum_1952 phosphoglucose isomerase; Belongs to the GPI family. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.981 |
| AEH22408.1 | pfkA | TOPB45_0294 | TOPB45_1305 | PFAM: Phosphoglucose isomerase (PGI); KEGG: sfu:Sfum_1952 phosphoglucose isomerase; Belongs to the GPI family. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily. | 0.988 |
| AEH22408.1 | pgk | TOPB45_0294 | TOPB45_0105 | PFAM: Phosphoglucose isomerase (PGI); KEGG: sfu:Sfum_1952 phosphoglucose isomerase; Belongs to the GPI family. | HAMAP: Phosphoglycerate kinase; KEGG: ddf:DEFDS_1892 phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | 0.940 |
| AEH22408.1 | tal | TOPB45_0294 | TOPB45_0487 | PFAM: Phosphoglucose isomerase (PGI); KEGG: sfu:Sfum_1952 phosphoglucose isomerase; Belongs to the GPI family. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | 0.970 |
| AEH22408.1 | tpiA | TOPB45_0294 | TOPB45_0104 | PFAM: Phosphoglucose isomerase (PGI); KEGG: sfu:Sfum_1952 phosphoglucose isomerase; Belongs to the GPI family. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.988 |
| AEH22433.1 | AEH22408.1 | TOPB45_0321 | TOPB45_0294 | TIGRFAM: Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; KEGG: dte:Dester_1366 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: Mannose-6-phosphate isomerase, type II, C-terminal; Nucleotidyl transferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | PFAM: Phosphoglucose isomerase (PGI); KEGG: sfu:Sfum_1952 phosphoglucose isomerase; Belongs to the GPI family. | 0.952 |
| AEH22433.1 | AEH22515.1 | TOPB45_0321 | TOPB45_0411 | TIGRFAM: Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; KEGG: dte:Dester_1366 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: Mannose-6-phosphate isomerase, type II, C-terminal; Nucleotidyl transferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Glucokinase; KEGG: plu:plu1405 glucokinase; PFAM: Glucokinase; Belongs to the bacterial glucokinase family. | 0.408 |
| AEH22433.1 | AEH23481.1 | TOPB45_0321 | TOPB45_1400 | TIGRFAM: Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; KEGG: dte:Dester_1366 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: Mannose-6-phosphate isomerase, type II, C-terminal; Nucleotidyl transferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | 1-deoxy-D-xylulose-5-phosphate synthase; KEGG: sfu:Sfum_1302 transketolase; PFAM: Transketolase, N-terminal; Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal. | 0.481 |
| AEH22433.1 | pfkA | TOPB45_0321 | TOPB45_1305 | TIGRFAM: Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; KEGG: dte:Dester_1366 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: Mannose-6-phosphate isomerase, type II, C-terminal; Nucleotidyl transferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily. | 0.930 |
| AEH22433.1 | tpiA | TOPB45_0321 | TOPB45_0104 | TIGRFAM: Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; KEGG: dte:Dester_1366 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: Mannose-6-phosphate isomerase, type II, C-terminal; Nucleotidyl transferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.430 |
| AEH22515.1 | AEH22408.1 | TOPB45_0411 | TOPB45_0294 | Glucokinase; KEGG: plu:plu1405 glucokinase; PFAM: Glucokinase; Belongs to the bacterial glucokinase family. | PFAM: Phosphoglucose isomerase (PGI); KEGG: sfu:Sfum_1952 phosphoglucose isomerase; Belongs to the GPI family. | 0.935 |
| AEH22515.1 | AEH22433.1 | TOPB45_0411 | TOPB45_0321 | Glucokinase; KEGG: plu:plu1405 glucokinase; PFAM: Glucokinase; Belongs to the bacterial glucokinase family. | TIGRFAM: Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; KEGG: dte:Dester_1366 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: Mannose-6-phosphate isomerase, type II, C-terminal; Nucleotidyl transferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.408 |
| AEH22515.1 | AEH23136.1 | TOPB45_0411 | TOPB45_1042 | Glucokinase; KEGG: plu:plu1405 glucokinase; PFAM: Glucokinase; Belongs to the bacterial glucokinase family. | TIGRFAM: Pyruvate kinase; KEGG: pmx:PERMA_0022 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; Belongs to the pyruvate kinase family. | 0.463 |
| AEH22515.1 | AEH23481.1 | TOPB45_0411 | TOPB45_1400 | Glucokinase; KEGG: plu:plu1405 glucokinase; PFAM: Glucokinase; Belongs to the bacterial glucokinase family. | 1-deoxy-D-xylulose-5-phosphate synthase; KEGG: sfu:Sfum_1302 transketolase; PFAM: Transketolase, N-terminal; Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal. | 0.866 |
| AEH22515.1 | tal | TOPB45_0411 | TOPB45_0487 | Glucokinase; KEGG: plu:plu1405 glucokinase; PFAM: Glucokinase; Belongs to the bacterial glucokinase family. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | 0.837 |