close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH22413.1KEGG: ddf:DEFDS_2147 negative regulator of flagellin synthesis FlgM; TIGRFAM: flagellar biosynthesis anti-sigma factor protein FlgM; PFAM: Anti-sigma-28 factor, FlgM. (103 aa)    
Predicted Functional Partners:
AEH23407.1
KEGG: dak:DaAHT2_1725 RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; TIGRFAM: RNA polymerase sigma factor, FliA/WhiG; RNA polymerase sigma-70; PFAM: RNA polymerase sigma-70 region 4; RNA polymerase sigma-70 region 2; RNA polymerase sigma-70 region 3.
  
 0.995
AEH23707.1
KEGG: tye:THEYE_A1509 flagellar protein FliS; TIGRFAM: Flagellar protein FliS; PFAM: Flagellar protein FliS.
  
 
 0.979
AEH23643.1
KEGG: dak:DaAHT2_2345 flagellar hook-associated protein FlgK; TIGRFAM: Flagellar hook-associated protein, FlgK; PFAM: Protein of unknown function DUF1078, C-terminal.
  
  
 0.919
AEH23708.1
Flagellar hook-associated 2 domain-containing protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
  
  
 0.913
AEH23418.1
Flagellar basal body-associated protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
  
  
 0.894
AEH22173.1
Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
  
  
 0.875
AEH23143.1
KEGG: rrs:RoseRS_0892 WD-40 repeat-containing protein; PFAM: WD40 repeat, subgroup; SMART: WD40 repeat.
  
 
 0.870
AEH22204.1
Flagellar hook capping protein; Required for flagellar hook formation. May act as a scaffolding protein.
  
  
 0.864
AEH22174.1
KEGG: dak:DaAHT2_1190 flagellar basal-body rod protein FlgC; TIGRFAM: Flagellar basal-body rod protein FlgC; PFAM: Protein of unknown function DUF1078, C-terminal.
  
  
 0.863
AEH23548.1
KEGG: dpr:Despr_1818 CheA signal transduction histidine kinase; PFAM: Signal transduction response regulator, receiver region; ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup, homodimeric; Signal transduction histidine kinase, phosphotransfer (Hpt) region; CheW-like protein; SMART: CheW-like protein; ATP-binding region, ATPase-like; Signal transduction histidine kinase, phosphotransfer (Hpt) region; Signal transduction response regulator, receiver region.
  
 
 0.828
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
Server load: low (24%) [HD]