Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH22414.1rfaE bifunctional protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. (404 aa)    
Predicted Functional Partners:
AEH22245.1
PfkB domain protein; PFAM: Carbohydrate/purine kinase; KEGG: lba:Lebu_0628 RfaE bifunctional protein.
 
     0.975
gmhA
Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily.
   
 0.963
AEH23252.1
TIGRFAM: Histidinol-phosphate phosphatase; HAD-superfamily hydrolase, subfamily IIIA; KEGG: dpr:Despr_1621 histidinol-phosphate phosphatase family protein; PFAM: Haloacid dehalogenase-like hydrolase.
   
 0.913
AEH22415.1
PFAM: Phosphoribosyltransferase; KEGG: cdl:CDR20291_0132 putative phosphoribosyl transferase.
     
 0.833
AEH22416.1
Peptidase T-like protein; KEGG: dat:HRM2_27370 PepT; TIGRFAM: Peptidase M20B, peptidase T; PFAM: Peptidase M20, dimerisation; Peptidase M20.
       0.816
AEH22417.1
Acylphosphatase; KEGG: sfu:Sfum_1427 acylphosphatase; HAMAP: Acylphosphatase; PFAM: Acylphosphatase-like.
       0.811
AEH22240.1
KEGG: maq:Maqu_0789 lipopolysaccharide heptosyltransferase II; TIGRFAM: Lipopolysaccharide heptosyltransferase II; PFAM: Glycosyl transferase, family 9.
 
   
 0.777
AEH23253.1
KEGG: tye:THEYE_A0945 lipopolysaccharide heptosyltransferase II; TIGRFAM: Lipopolysaccharide heptosyltransferase I; Lipopolysaccharide heptosyltransferase II; PFAM: Glycosyl transferase, family 9.
 
   
 0.776
hldD
ADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
 
  
 0.644
AEH22483.1
CoA-disulfide reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: dps:DP2890 NADH oxidase; SMART: Rhodanese-like.
   
  
 0.582
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
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