Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH22425.1TIGRFAM: Ribonucleoside-triphosphate reductase, anaerobic-like; PFAM: Radical SAM; KEGG: pca:Pcar_2732 pyruvate-formate lyase-activating enzyme; SMART: Elongator protein 3/MiaB/NifB. (230 aa)    
Predicted Functional Partners:
AEH22806.1
TIGRFAM: Ribonucleoside-triphosphate reductase, anaerobic; Intein splicing site; PFAM: ATP-cone; KEGG: cow:Calow_0403 anaerobic ribonucleoside-triphosphate reductase; SMART: Hedgehog/intein hint, N-terminal.
  
 0.899
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
       0.777
AEH22805.1
Hypothetical protein; KEGG: kol:Kole_0530 anaerobic ribonucleoside triphosphate reductase.
 
  
 0.767
AEH22424.1
PFAM: Protein of unknown function DUF125, transmembrane; KEGG: sta:STHERM_c17420 hypothetical protein.
       0.671
AEH22423.1
KEGG: dte:Dester_1082 hypothetical protein.
       0.470
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
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