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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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co-expression
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AEH22484.1Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family. (636 aa)    
Predicted Functional Partners:
AEH23270.1
FeoA family protein; PFAM: Ferrous iron transporter, FeoA subunit; KEGG: tye:THEYE_A0965 hypothetical protein.
  
  
 0.808
AEH22485.1
PFAM: Peptidase M24, structural domain; Creatinase; KEGG: aae:aq_1535 Xaa-Pro dipeptidase.
  
    0.777
AEH23268.1
TIGRFAM: Diguanylate cyclase, predicted; PFAM: Diguanylate cyclase, predicted; Ferrous iron transporter, FeoA subunit; KEGG: glo:Glov_1783 diguanylate cyclase; SMART: Diguanylate cyclase, predicted.
  
  
 0.599
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
     
 0.595
trpE
Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
     
 0.592
AEH22483.1
CoA-disulfide reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: dps:DP2890 NADH oxidase; SMART: Rhodanese-like.
     
 0.580
hisS
PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved region; Anticodon-binding; TIGRFAM: Histidyl-tRNA synthetase, class IIa, subgroup; HAMAP: Histidyl-tRNA synthetase, class IIa, subgroup; KEGG: has:Halsa_1638 histidyl-tRNA synthetase.
       0.577
AEH22625.1
FeoA family protein; PFAM: Ferrous iron transporter, FeoA subunit; KEGG: hth:HTH_0317 ferrous iron transport protein A.
  
  
 0.577
AEH23267.1
FeoA family protein; PFAM: Ferrous iron transporter, FeoA subunit; KEGG: cte:CT1744 hypothetical protein.
   
  
 0.572
AEH22479.1
SMART: Phospholipid/glycerol acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferase; KEGG: dak:DaAHT2_0301 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: Phospholipid/glycerol acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
       0.565
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
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