Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH22505.1TIGRFAM: UDP-glucose 4-epimerase; KEGG: aae:aq_1069 UDP-glucose-4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (327 aa)    
Predicted Functional Partners:
AEH23588.1
KEGG: ttm:Tthe_2060 UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase.
 
  
 0.953
AEH23577.1
TIGRFAM: Nucleotide sugar dehydrogenase; KEGG: cni:Calni_2007 nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase, N-terminal; UDP-glucose/GDP-mannose dehydrogenase, dimerisation; UDP-glucose/GDP-mannose dehydrogenase, C-terminal.
  
 
 0.937
AEH22446.1
TIGRFAM: UDP-galactopyranose mutase; KEGG: sul:SYO3AOP1_1566 UDP-galactopyranose mutase; PFAM: UDP-galactopyranose mutase, C-terminal; Glucose-methanol-choline oxidoreductase, N-terminal.
    
 0.924
AEH22433.1
TIGRFAM: Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; KEGG: dte:Dester_1366 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: Mannose-6-phosphate isomerase, type II, C-terminal; Nucleotidyl transferase; Belongs to the mannose-6-phosphate isomerase type 2 family.
 
 
 0.920
AEH23484.1
PFAM: Nucleotidyl transferase; KEGG: dak:DaAHT2_0857 nucleotidyl transferase.
  
 
 0.847
AEH22457.1
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
    
 0.823
fhs
HAMAP: Formate-tetrahydrofolate ligase, FTHFS; KEGG: dak:DaAHT2_0837 formate--tetrahydrofolate ligase; PFAM: Formate-tetrahydrofolate ligase, FTHFS; Belongs to the formate--tetrahydrofolate ligase family.
  
  
 0.786
folD
Bifunctional protein folD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
       0.757
AEH22501.1
KEGG: dal:Dalk_2780 hypothetical protein.
       0.650
AEH22500.1
PFAM: Methylenetetrahydrofolate reductase; KEGG: adg:Adeg_0345 methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
       0.630
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
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