Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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AEH22507.1Deoxyguanosinetriphosphate triphosphohydrolase-like protein; SMART: Metal-dependent phosphohydrolase, HD region; TIGRFAM: Deoxyguanosinetriphosphate triphosphohydrolase; KEGG: ddf:DEFDS_0159 deoxyguanosinetriphosphate triphosphohydrolase; HAMAP: Deoxyguanosinetriphosphate triphosphohydrolase-like protein; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; Belongs to the dGTPase family. Type 2 subfamily. (359 aa)    
Predicted Functional Partners:
surE
Multifunctional protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
  0.911
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
   
 
  0.901
AEH23250.1
Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
     
  0.900
AEH22508.1
KEGG: adg:Adeg_0900 formyl transferase domain protein.
       0.802
AEH22509.1
Hypothetical protein; KEGG: dbr:Deba_2428 tol-pal system protein YbgF.
       0.787
AEH22506.1
KEGG: sat:SYN_02529 single-stranded DNA-specific exonuclease; TIGRFAM: Bacterial RecJ exonuclease; PFAM: Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1.
       0.779
AEH22505.1
TIGRFAM: UDP-glucose 4-epimerase; KEGG: aae:aq_1069 UDP-glucose-4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
       0.577
fhs
HAMAP: Formate-tetrahydrofolate ligase, FTHFS; KEGG: dak:DaAHT2_0837 formate--tetrahydrofolate ligase; PFAM: Formate-tetrahydrofolate ligase, FTHFS; Belongs to the formate--tetrahydrofolate ligase family.
       0.560
folD
Bifunctional protein folD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
       0.542
AEH22500.1
PFAM: Methylenetetrahydrofolate reductase; KEGG: adg:Adeg_0345 methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
       0.464
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
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