Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH22533.1PFAM: Uncharacterised conserved protein UCP016719; KEGG: sfu:Sfum_0535 hypothetical protein. (394 aa)    
Predicted Functional Partners:
AEH22725.1
PFAM: Beta-lactamase-related; KEGG: dal:Dalk_3805 beta-lactamase.
  
 0.957
AEH22532.1
KEGG: din:Selin_2214 cell wall hydrolase/autolysin; PFAM: Cell wall hydrolase/autolysin, catalytic; Peptidoglycan-binding lysin domain; SMART: Cell wall hydrolase/autolysin, catalytic; Peptidoglycan-binding Lysin subgroup.
       0.821
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
       0.801
AEH22534.1
PFAM: Phosphoesterase, RecJ-like; KEGG: dak:DaAHT2_1369 phosphoesterase RecJ domain protein.
       0.800
mutS
DNA mismatch repair protein mutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
       0.786
AEH22349.1
Beta-N-acetylhexosaminidase; KEGG: ctc:CTC02158 putative anhydromuramoyl-peptide exo-beta-N-acetylglucosaminidase; PFAM: Glycoside hydrolase, family 3, N-terminal.
 
    0.777
obg
GTPase obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
       0.777
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
       0.775
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
       0.699
AEH22537.1
DNA polymerase III, alpha subunit; SMART: Polymerase/histidinol phosphatase, N-terminal; TIGRFAM: DNA polymerase III, alpha subunit; KEGG: dte:Dester_1146 DNA polymerase III, alpha subunit; PFAM: Bacterial DNA polymerase III, alpha subunit; PHP, C-terminal; Nucleic acid binding, OB-fold, tRNA/helicase-type.
       0.595
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
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