Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rlmHRibosomal RNA large subunit methyltransferase H; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (156 aa)    
Predicted Functional Partners:
rsfS
Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
  
 0.847
AEH22541.1
PFAM: Histone deacetylase superfamily; KEGG: sat:SYN_00740 histone deacetylase family protein.
       0.773
AEH22542.1
PFAM: Secretion protein HlyD; KEGG: tye:THEYE_A1628 HlyD family secretion protein, putative; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
       0.773
AEH22543.1
Monosaccharide-transporting ATPase; PFAM: ABC transporter-like; KEGG: tye:THEYE_A1627 ABC transporter ATP-binding component; SMART: ATPase, AAA+ type, core.
       0.773
AEH22544.1
PFAM: ABC-2 type transporter; KEGG: tye:THEYE_A1624 ATPase component ABC-type multidrug transport system.
       0.773
AEH22545.1
PFAM: ABC-2 type transporter; KEGG: tye:THEYE_A1623 ABC-2 type transporter.
       0.773
AEH22539.1
PFAM: Organic solvent tolerance protein; KEGG: dps:DP3010 organic solvent tolerance protein (OstA).
       0.772
AEH22546.1
PFAM: Protein of unknown function DUF369; KEGG: tye:THEYE_A0257 hypothetical protein.
       0.757
AEH22538.1
PFAM: Rubrerythrin; KEGG: tye:THEYE_A0129 methyltransferase.
       0.717
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
  
 0.671
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.