Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH22541.1PFAM: Histone deacetylase superfamily; KEGG: sat:SYN_00740 histone deacetylase family protein. (350 aa)    
Predicted Functional Partners:
AEH23144.1
AAA ATPase central domain protein; KEGG: cac:CA_C0602 ATP-dependent zinc metallopeptidase FtsH (cell dividion protein); PFAM: ATPase, AAA-type, core; SMART: ATPase, AAA+ type, core.
    
 0.836
AEH23180.1
AAA ATPase central domain protein; KEGG: msk:Msui08060 cell division protease FtsH-like protein; PFAM: ATPase, AAA-type, core; SMART: ATPase, AAA+ type, core.
    
 0.836
AEH23141.1
Helicase domain-containing protein; KEGG: tal:Thal_0495 helicase; PFAM: DNA/RNA helicase, C-terminal; SNF2-related; SMART: DNA/RNA helicase, C-terminal; DEAD-like helicase, N-terminal.
    
 0.832
AEH23143.1
KEGG: rrs:RoseRS_0892 WD-40 repeat-containing protein; PFAM: WD40 repeat, subgroup; SMART: WD40 repeat.
  
 0.829
AEH22596.1
KEGG: nam:NAMH_0804 NAD-dependent deacetylase; HAMAP: NAD-dependent deacetylase; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2.
    
 0.825
dnaK
Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
    
 0.806
AEH22615.1
Hypothetical protein.
    
 
 0.800
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
   0.797
atpD
ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family.
    
 0.795
AEH22539.1
PFAM: Organic solvent tolerance protein; KEGG: dps:DP3010 organic solvent tolerance protein (OstA).
       0.791
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
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