Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH22562.1Histidine kinase; KEGG: gmc:GY4MC1_1620 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region. (357 aa)    
Predicted Functional Partners:
AEH22561.1
KEGG: cch:Cag_0435 two component transcriptional regulator; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver region.
 
 
 0.968
AEH23402.1
KEGG: pbs:Plabr_1783 response regulator receiver protein; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region.
  
 
 0.868
AEH23656.1
PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS; PFAM: ATP-binding region, ATPase-like; Signal transduction response regulator, receiver region; KEGG: atu:Atu1362 two component sensor kinase; SMART: ATP-binding region, ATPase-like; PAS; Signal transduction response regulator, receiver region.
  
 
   0.781
AEH23406.1
Response regulator receiver protein; KEGG: dat:HRM2_37360 CheY; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region.
  
 
   0.756
AEH22563.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: Diguanylate cyclase, predicted; PAS; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; KEGG: saf:SULAZ_0401 PAS fold family protein; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; PAS.
  
 
 0.486
AEH23548.1
KEGG: dpr:Despr_1818 CheA signal transduction histidine kinase; PFAM: Signal transduction response regulator, receiver region; ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup, homodimeric; Signal transduction histidine kinase, phosphotransfer (Hpt) region; CheW-like protein; SMART: CheW-like protein; ATP-binding region, ATPase-like; Signal transduction histidine kinase, phosphotransfer (Hpt) region; Signal transduction response regulator, receiver region.
 
 
 
 0.457
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
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