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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH22577.1KEGG: dak:DaAHT2_1957 DNA repair protein RadC; TIGRFAM: DNA repair, RadC-like; PFAM: DNA repair, RadC-like; Belongs to the UPF0758 family. (247 aa)    
Predicted Functional Partners:
tadA
CMP/dCMP deaminase zinc-binding protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
     
 0.813
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
       0.799
AEH22578.1
PFAM: Protein of unknown function DUF1239.
       0.780
AEH22579.1
3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; TIGRFAM: Phosphatase KdsC; HAD-superfamily hydrolase, subfamily IIIA; KEGG: tye:THEYE_A0223 bifunctional protein HldE; PFAM: Haloacid dehalogenase-like hydrolase.
       0.780
kdsA
2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA; TIGRFAM: 3-deoxy-8-phosphooctulonate synthase; HAMAP: 3-deoxy-8-phosphooctulonate synthase; KEGG: hya:HY04AAS1_1603 2-dehydro-3-deoxyphosphooctonate aldolase.
       0.780
AEH23633.1
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
  
  
 0.766
AEH22415.1
PFAM: Phosphoribosyltransferase; KEGG: cdl:CDR20291_0132 putative phosphoribosyl transferase.
 
    0.751
mutL
DNA mismatch repair protein mutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
 
   
 0.653
AEH23620.1
KEGG: sep:SE1274 ComEC late competence protein 3; TIGRFAM: Competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein.
 
  
 0.587
mutS
DNA mismatch repair protein mutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
 
   
 0.567
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
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