| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEH22595.1 | AEH22596.1 | TOPB45_0493 | TOPB45_0494 | Regulatory protein, FmdB family; KEGG: ddf:DEFDS_1168 hypothetical protein; TIGRFAM: Regulatory protein, FmdB, putative; PFAM: Regulatory protein, FmdB, putative. | KEGG: nam:NAMH_0804 NAD-dependent deacetylase; HAMAP: NAD-dependent deacetylase; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2. | 0.598 |
| AEH22595.1 | AEH22597.1 | TOPB45_0493 | TOPB45_0495 | Regulatory protein, FmdB family; KEGG: ddf:DEFDS_1168 hypothetical protein; TIGRFAM: Regulatory protein, FmdB, putative; PFAM: Regulatory protein, FmdB, putative. | PFAM: Divalent ion tolerance protein, CutA1; KEGG: das:Daes_1411 CutA1 divalent ion tolerance protein. | 0.598 |
| AEH22595.1 | AEH22598.1 | TOPB45_0493 | TOPB45_0496 | Regulatory protein, FmdB family; KEGG: ddf:DEFDS_1168 hypothetical protein; TIGRFAM: Regulatory protein, FmdB, putative; PFAM: Regulatory protein, FmdB, putative. | Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | 0.598 |
| AEH22595.1 | hisF | TOPB45_0493 | TOPB45_0492 | Regulatory protein, FmdB family; KEGG: ddf:DEFDS_1168 hypothetical protein; TIGRFAM: Regulatory protein, FmdB, putative; PFAM: Regulatory protein, FmdB, putative. | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.570 |
| AEH22596.1 | AEH22595.1 | TOPB45_0494 | TOPB45_0493 | KEGG: nam:NAMH_0804 NAD-dependent deacetylase; HAMAP: NAD-dependent deacetylase; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2. | Regulatory protein, FmdB family; KEGG: ddf:DEFDS_1168 hypothetical protein; TIGRFAM: Regulatory protein, FmdB, putative; PFAM: Regulatory protein, FmdB, putative. | 0.598 |
| AEH22596.1 | AEH22597.1 | TOPB45_0494 | TOPB45_0495 | KEGG: nam:NAMH_0804 NAD-dependent deacetylase; HAMAP: NAD-dependent deacetylase; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2. | PFAM: Divalent ion tolerance protein, CutA1; KEGG: das:Daes_1411 CutA1 divalent ion tolerance protein. | 0.773 |
| AEH22596.1 | AEH22598.1 | TOPB45_0494 | TOPB45_0496 | KEGG: nam:NAMH_0804 NAD-dependent deacetylase; HAMAP: NAD-dependent deacetylase; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2. | Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | 0.773 |
| AEH22596.1 | AEH22599.1 | TOPB45_0494 | TOPB45_0497 | KEGG: nam:NAMH_0804 NAD-dependent deacetylase; HAMAP: NAD-dependent deacetylase; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2. | Formate dehydrogenase, alpha subunit; PFAM: Molybdopterin oxidoreductase Fe4S4 region; Molybdopterin oxidoreductase; Molydopterin dinucleotide-binding region; manually curated; KEGG: tye:THEYE_A0891 formate dehydrogenase, alpha subunit, selenocysteine-containing; TIGRFAM: Formate dehydrogenase, alpha subunit, anaerobic; Twin-arginine translocation pathway, signal sequence; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.465 |
| AEH22596.1 | AEH22600.1 | TOPB45_0494 | TOPB45_0498 | KEGG: nam:NAMH_0804 NAD-dependent deacetylase; HAMAP: NAD-dependent deacetylase; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2. | PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: tye:THEYE_A0893 nitrate-inducible formate dehydrogenase, beta subunit. | 0.440 |
| AEH22596.1 | hisF | TOPB45_0494 | TOPB45_0492 | KEGG: nam:NAMH_0804 NAD-dependent deacetylase; HAMAP: NAD-dependent deacetylase; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2. | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.451 |
| AEH22597.1 | AEH22595.1 | TOPB45_0495 | TOPB45_0493 | PFAM: Divalent ion tolerance protein, CutA1; KEGG: das:Daes_1411 CutA1 divalent ion tolerance protein. | Regulatory protein, FmdB family; KEGG: ddf:DEFDS_1168 hypothetical protein; TIGRFAM: Regulatory protein, FmdB, putative; PFAM: Regulatory protein, FmdB, putative. | 0.598 |
| AEH22597.1 | AEH22596.1 | TOPB45_0495 | TOPB45_0494 | PFAM: Divalent ion tolerance protein, CutA1; KEGG: das:Daes_1411 CutA1 divalent ion tolerance protein. | KEGG: nam:NAMH_0804 NAD-dependent deacetylase; HAMAP: NAD-dependent deacetylase; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2. | 0.773 |
| AEH22597.1 | AEH22598.1 | TOPB45_0495 | TOPB45_0496 | PFAM: Divalent ion tolerance protein, CutA1; KEGG: das:Daes_1411 CutA1 divalent ion tolerance protein. | Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | 0.773 |
| AEH22597.1 | AEH22599.1 | TOPB45_0495 | TOPB45_0497 | PFAM: Divalent ion tolerance protein, CutA1; KEGG: das:Daes_1411 CutA1 divalent ion tolerance protein. | Formate dehydrogenase, alpha subunit; PFAM: Molybdopterin oxidoreductase Fe4S4 region; Molybdopterin oxidoreductase; Molydopterin dinucleotide-binding region; manually curated; KEGG: tye:THEYE_A0891 formate dehydrogenase, alpha subunit, selenocysteine-containing; TIGRFAM: Formate dehydrogenase, alpha subunit, anaerobic; Twin-arginine translocation pathway, signal sequence; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.478 |
| AEH22597.1 | AEH22600.1 | TOPB45_0495 | TOPB45_0498 | PFAM: Divalent ion tolerance protein, CutA1; KEGG: das:Daes_1411 CutA1 divalent ion tolerance protein. | PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: tye:THEYE_A0893 nitrate-inducible formate dehydrogenase, beta subunit. | 0.439 |
| AEH22597.1 | AEH22643.1 | TOPB45_0495 | TOPB45_0541 | PFAM: Divalent ion tolerance protein, CutA1; KEGG: das:Daes_1411 CutA1 divalent ion tolerance protein. | Desulfoferrodoxin; KEGG: dma:DMR_17610 desulfoferrodoxin; TIGRFAM: Desulfoferrodoxin; Desulfoferrodoxin Dfx; Desulfoferrodoxin, ferrous iron-binding region; PFAM: Desulfoferrodoxin, ferrous iron-binding region; Desulfoferrodoxin Dfx. | 0.444 |
| AEH22597.1 | hisF | TOPB45_0495 | TOPB45_0492 | PFAM: Divalent ion tolerance protein, CutA1; KEGG: das:Daes_1411 CutA1 divalent ion tolerance protein. | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.463 |
| AEH22598.1 | AEH22595.1 | TOPB45_0496 | TOPB45_0493 | Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | Regulatory protein, FmdB family; KEGG: ddf:DEFDS_1168 hypothetical protein; TIGRFAM: Regulatory protein, FmdB, putative; PFAM: Regulatory protein, FmdB, putative. | 0.598 |
| AEH22598.1 | AEH22596.1 | TOPB45_0496 | TOPB45_0494 | Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | KEGG: nam:NAMH_0804 NAD-dependent deacetylase; HAMAP: NAD-dependent deacetylase; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2. | 0.773 |
| AEH22598.1 | AEH22597.1 | TOPB45_0496 | TOPB45_0495 | Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | PFAM: Divalent ion tolerance protein, CutA1; KEGG: das:Daes_1411 CutA1 divalent ion tolerance protein. | 0.773 |