Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH22608.1TIGRFAM: FO synthase, subunit 2; PFAM: Radical SAM; KEGG: tam:Theam_0970 radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB. (370 aa)    
Predicted Functional Partners:
mqnA
Protein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).
 
  
 0.978
AEH22384.1
S-adenosylhomocysteine deaminase; KEGG: dpr:Despr_1798 amidohydrolase; PFAM: Amidohydrolase 1.
 
  
  0.927
mqnD
Hypothetical protein; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily.
 
   
 0.790
thiC
Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
  
  
 0.777
AEH22606.1
Hypothetical protein.
       0.777
AEH22607.1
KEGG: tye:THEYE_A1135 hypothetical protein.
       0.777
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
  
 0.766
AEH22609.1
PFAM: Glycosyl transferase, family 2; KEGG: app:CAP2UW1_3097 family 2 glycosyl transferase.
     
 0.756
AEH22611.1
KEGG: pvi:Cvib_0642 hypothetical protein.
     
 0.753
AEH22610.1
Hypothetical protein; KEGG: pca:Pcar_1265 putative LPS biosynthesis enzyme.
       0.752
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
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