Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEH22661.1PFAM: Peptidase U62, modulator of DNA gyrase; KEGG: tye:THEYE_A0931 protein TldD. (459 aa)    
Predicted Functional Partners:
AEH22660.1
PfkB domain protein; PFAM: Carbohydrate/purine kinase; KEGG: apo:Arcpr_0268 PfkB domain protein.
       0.796
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
       0.786
AEH22663.1
Menaquinone biosynthesis decarboxylase, SCO4490 family; KEGG: ddf:DEFDS_1642 3-octaprenyl-4-hydroxybenzoate carboxy-lyase UbiD; TIGRFAM: menaquinone biosynthesis decarboxylase, SCO4490 family; Carboxylyase-related; PFAM: Carboxylyase-related; Belongs to the UbiD family.
       0.775
AEH22664.1
KEGG: dak:DaAHT2_0278 phosphodiesterase, MJ0936 family; TIGRFAM: Uncharacterised protein family UPF0025; PFAM: Metallophosphoesterase.
       0.756
proS
Prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]
       0.716
lpxD
UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
       0.716
AEH22659.1
KEGG: atm:ANT_26280 hypothetical protein.
       0.457
AEH22657.1
KEGG: deb:DehaBAV1_1373 beta-lactamase domain-containing protein.
 
     0.441
AEH22658.1
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
       0.438
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.