| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEH22691.1 | AEH22693.1 | TOPB45_0589 | TOPB45_0591 | UPF0161 protein yidD; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | Hypothetical protein; KEGG: slp:Slip_2381 single-stranded nucleic acid binding R3H domain protein. | 0.892 |
| AEH22691.1 | AEH22695.1 | TOPB45_0589 | TOPB45_0593 | UPF0161 protein yidD; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | KEGG: tam:Theam_0093 5-oxoprolinase (ATP-hydrolyzing); PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase, N-terminal. | 0.709 |
| AEH22691.1 | AEH22697.1 | TOPB45_0589 | TOPB45_0595 | UPF0161 protein yidD; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | KEGG: aae:aq_1960 HMP-P kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | 0.726 |
| AEH22691.1 | gatC | TOPB45_0589 | TOPB45_0596 | UPF0161 protein yidD; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. | 0.722 |
| AEH22691.1 | mnmE | TOPB45_0589 | TOPB45_0592 | UPF0161 protein yidD; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | tRNA modification GTPase mnmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.764 |
| AEH22691.1 | rnpA | TOPB45_0589 | TOPB45_0588 | UPF0161 protein yidD; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.984 |
| AEH22691.1 | rpmH | TOPB45_0589 | TOPB45_0587 | UPF0161 protein yidD; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | TIGRFAM: Ribosomal protein L34; HAMAP: 50S ribosomal protein L34; KEGG: tme:Tmel_1628 50S ribosomal protein L34; PFAM: Ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family. | 0.836 |
| AEH22691.1 | secE | TOPB45_0589 | TOPB45_0170 | UPF0161 protein yidD; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.778 |
| AEH22691.1 | serS | TOPB45_0589 | TOPB45_1626 | UPF0161 protein yidD; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | Seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). | 0.747 |
| AEH22691.1 | yidC | TOPB45_0589 | TOPB45_0590 | UPF0161 protein yidD; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | Membrane protein oxaA; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.956 |
| AEH22693.1 | AEH22691.1 | TOPB45_0591 | TOPB45_0589 | Hypothetical protein; KEGG: slp:Slip_2381 single-stranded nucleic acid binding R3H domain protein. | UPF0161 protein yidD; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | 0.892 |
| AEH22693.1 | AEH22695.1 | TOPB45_0591 | TOPB45_0593 | Hypothetical protein; KEGG: slp:Slip_2381 single-stranded nucleic acid binding R3H domain protein. | KEGG: tam:Theam_0093 5-oxoprolinase (ATP-hydrolyzing); PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase, N-terminal. | 0.773 |
| AEH22693.1 | AEH22697.1 | TOPB45_0591 | TOPB45_0595 | Hypothetical protein; KEGG: slp:Slip_2381 single-stranded nucleic acid binding R3H domain protein. | KEGG: aae:aq_1960 HMP-P kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | 0.788 |
| AEH22693.1 | gatC | TOPB45_0591 | TOPB45_0596 | Hypothetical protein; KEGG: slp:Slip_2381 single-stranded nucleic acid binding R3H domain protein. | Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. | 0.788 |
| AEH22693.1 | mnmE | TOPB45_0591 | TOPB45_0592 | Hypothetical protein; KEGG: slp:Slip_2381 single-stranded nucleic acid binding R3H domain protein. | tRNA modification GTPase mnmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.831 |
| AEH22693.1 | rnpA | TOPB45_0591 | TOPB45_0588 | Hypothetical protein; KEGG: slp:Slip_2381 single-stranded nucleic acid binding R3H domain protein. | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.910 |
| AEH22693.1 | rpmH | TOPB45_0591 | TOPB45_0587 | Hypothetical protein; KEGG: slp:Slip_2381 single-stranded nucleic acid binding R3H domain protein. | TIGRFAM: Ribosomal protein L34; HAMAP: 50S ribosomal protein L34; KEGG: tme:Tmel_1628 50S ribosomal protein L34; PFAM: Ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family. | 0.756 |
| AEH22693.1 | yidC | TOPB45_0591 | TOPB45_0590 | Hypothetical protein; KEGG: slp:Slip_2381 single-stranded nucleic acid binding R3H domain protein. | Membrane protein oxaA; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.949 |
| AEH22695.1 | AEH22691.1 | TOPB45_0593 | TOPB45_0589 | KEGG: tam:Theam_0093 5-oxoprolinase (ATP-hydrolyzing); PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase, N-terminal. | UPF0161 protein yidD; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | 0.709 |
| AEH22695.1 | AEH22693.1 | TOPB45_0593 | TOPB45_0591 | KEGG: tam:Theam_0093 5-oxoprolinase (ATP-hydrolyzing); PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase, N-terminal. | Hypothetical protein; KEGG: slp:Slip_2381 single-stranded nucleic acid binding R3H domain protein. | 0.773 |