Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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AEH22729.1Putative signal transduction protein with CBS domains; KEGG: tye:THEYE_A1360 CBS domain protein; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core. (132 aa)    
Predicted Functional Partners:
AEH22727.1
PFAM: Phosphate transporter; KEGG: tye:THEYE_A1362 sodium/phosphate symporter.
 
     0.801
AEH22728.1
Protein of unknown function DUF47; KEGG: tye:THEYE_A1361 hypothetical protein; TIGRFAM: Protein of unknown function DUF47; PFAM: Putitive phosphate transport regulator.
       0.752
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
  
    0.723
AEH22730.1
PFAM: Inositol monophosphatase; NUDIX hydrolase domain; KEGG: dak:DaAHT2_0139 inositol monophosphatase.
       0.541
AEH22731.1
TIGRFAM: Diguanylate cyclase, predicted; PFAM: Diguanylate cyclase, predicted; KEGG: dak:DaAHT2_1538 response regulator receiver modulated diguanylate cyclase; SMART: Diguanylate cyclase, predicted.
       0.541
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.507
AEH23336.1
KEGG: hth:HTH_0871 ferredoxin-dependent glutamate synthase; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal.
     
 0.502
AEH22563.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: Diguanylate cyclase, predicted; PAS; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; KEGG: saf:SULAZ_0401 PAS fold family protein; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; PAS.
     
 0.448
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
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