Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEH22738.1Acetate--CoA ligase; KEGG: reh:H16_A1616 acetyl-coenzyme A synthetase; PFAM: AMP-dependent synthetase/ligase. (691 aa)    
Predicted Functional Partners:
AEH22735.1
KEGG: tye:THEYE_A1654 acetyl-CoA synthetase; TIGRFAM: Acetyl coenzyme A synthetase (ADP forming), alpha domain; PFAM: CoA-binding; ATP-grasp fold, succinyl-CoA synthetase-type.
    
 0.950
AEH22498.1
TIGRFAM: CO dehydrogenase/acetyl-CoA synthase complex beta subunit; KEGG: dak:DaAHT2_0825 CO dehydrogenase/acetyl-CoA synthase complex, beta subunit; PFAM: CO dehydrogenase/acetyl-CoA synthase complex beta subunit.
  
 
 0.947
AEH22497.1
PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; Putative Fe-S cluster; Dihydropteroate synthase, DHPS; KEGG: dak:DaAHT2_0824 CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel.
  
 
 0.946
AEH23354.1
KEGG: dak:DaAHT2_0461 acetyl-CoA carboxylase; PFAM: Acetyl-CoA carboxylase, alpha subunit, conserved region.
    
 0.932
AEH22814.1
Pyruvate carboxylase; KEGG: rca:Rcas_2955 carbamoyl-phosphate synthase L chain ATP-binding; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthase, large subunit, N-terminal; Biotin carboxylase, C-terminal.
  
 0.913
AEH22774.1
3-methyl-2-oxobutanoate dehydrogenase (ferredoxin); KEGG: dbr:Deba_1953 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal.
  
 
 0.912
AEH23678.1
KEGG: dbr:Deba_3202 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal.
  
 
 0.912
AEH22324.1
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate). Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.910
AEH22825.1
TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase related; KEGG: sfu:Sfum_2174 putative alpha-isopropylmalate/homocitrate synthase family transferase; PFAM: 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain; Pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.910
AEH22773.1
2-oxoglutarate synthase; KEGG: chy:CHY_1971 putative keto/oxoacid ferredoxin oxidoreductase subunit beta; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding.
   
 
 0.909
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.