| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEH22272.1 | AEH22336.1 | TOPB45_0157 | TOPB45_0221 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | KEGG: aae:aq_052 4-hydroxybenzoate octaprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase related; PFAM: UbiA prenyltransferase; Belongs to the UbiA prenyltransferase family. | 0.529 |
| AEH22272.1 | mltG | TOPB45_0157 | TOPB45_0654 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.493 |
| AEH22336.1 | AEH22272.1 | TOPB45_0221 | TOPB45_0157 | KEGG: aae:aq_052 4-hydroxybenzoate octaprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase related; PFAM: UbiA prenyltransferase; Belongs to the UbiA prenyltransferase family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.529 |
| AEH22336.1 | mltG | TOPB45_0221 | TOPB45_0654 | KEGG: aae:aq_052 4-hydroxybenzoate octaprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase related; PFAM: UbiA prenyltransferase; Belongs to the UbiA prenyltransferase family. | Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.482 |
| AEH22353.1 | AEH22532.1 | TOPB45_0239 | TOPB45_0428 | KEGG: dak:DaAHT2_0246 penicillin-binding protein, 1A family; TIGRFAM: Penicillin-binding protein 1A; PFAM: Glycosyl transferase, family 51; Penicillin-binding protein, transpeptidase. | KEGG: din:Selin_2214 cell wall hydrolase/autolysin; PFAM: Cell wall hydrolase/autolysin, catalytic; Peptidoglycan-binding lysin domain; SMART: Cell wall hydrolase/autolysin, catalytic; Peptidoglycan-binding Lysin subgroup. | 0.586 |
| AEH22353.1 | mltG | TOPB45_0239 | TOPB45_0654 | KEGG: dak:DaAHT2_0246 penicillin-binding protein, 1A family; TIGRFAM: Penicillin-binding protein 1A; PFAM: Glycosyl transferase, family 51; Penicillin-binding protein, transpeptidase. | Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.604 |
| AEH22532.1 | AEH22353.1 | TOPB45_0428 | TOPB45_0239 | KEGG: din:Selin_2214 cell wall hydrolase/autolysin; PFAM: Cell wall hydrolase/autolysin, catalytic; Peptidoglycan-binding lysin domain; SMART: Cell wall hydrolase/autolysin, catalytic; Peptidoglycan-binding Lysin subgroup. | KEGG: dak:DaAHT2_0246 penicillin-binding protein, 1A family; TIGRFAM: Penicillin-binding protein 1A; PFAM: Glycosyl transferase, family 51; Penicillin-binding protein, transpeptidase. | 0.586 |
| AEH22532.1 | ftsZ | TOPB45_0428 | TOPB45_0948 | KEGG: din:Selin_2214 cell wall hydrolase/autolysin; PFAM: Cell wall hydrolase/autolysin, catalytic; Peptidoglycan-binding lysin domain; SMART: Cell wall hydrolase/autolysin, catalytic; Peptidoglycan-binding Lysin subgroup. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.525 |
| AEH22532.1 | mltG | TOPB45_0428 | TOPB45_0654 | KEGG: din:Selin_2214 cell wall hydrolase/autolysin; PFAM: Cell wall hydrolase/autolysin, catalytic; Peptidoglycan-binding lysin domain; SMART: Cell wall hydrolase/autolysin, catalytic; Peptidoglycan-binding Lysin subgroup. | Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.592 |
| AEH22753.1 | AEH22754.1 | TOPB45_0651 | TOPB45_0652 | Tetratricopeptide TPR_1 repeat-containing protein; PFAM: Tetratricopeptide TPR-1; Tetratricopeptide TPR2; KEGG: saf:SULAZ_1707 tetratricopeptide TPR_2 repeat protein. | KEGG: dak:DaAHT2_1673 heat repeat-containing PBS lyase. | 0.940 |
| AEH22753.1 | AEH22755.1 | TOPB45_0651 | TOPB45_0653 | Tetratricopeptide TPR_1 repeat-containing protein; PFAM: Tetratricopeptide TPR-1; Tetratricopeptide TPR2; KEGG: saf:SULAZ_1707 tetratricopeptide TPR_2 repeat protein. | KEGG: dps:DP1095 hypothetical protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SMART: Tetratricopeptide repeat. | 0.839 |
| AEH22753.1 | mltG | TOPB45_0651 | TOPB45_0654 | Tetratricopeptide TPR_1 repeat-containing protein; PFAM: Tetratricopeptide TPR-1; Tetratricopeptide TPR2; KEGG: saf:SULAZ_1707 tetratricopeptide TPR_2 repeat protein. | Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.576 |
| AEH22754.1 | AEH22753.1 | TOPB45_0652 | TOPB45_0651 | KEGG: dak:DaAHT2_1673 heat repeat-containing PBS lyase. | Tetratricopeptide TPR_1 repeat-containing protein; PFAM: Tetratricopeptide TPR-1; Tetratricopeptide TPR2; KEGG: saf:SULAZ_1707 tetratricopeptide TPR_2 repeat protein. | 0.940 |
| AEH22754.1 | AEH22755.1 | TOPB45_0652 | TOPB45_0653 | KEGG: dak:DaAHT2_1673 heat repeat-containing PBS lyase. | KEGG: dps:DP1095 hypothetical protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SMART: Tetratricopeptide repeat. | 0.839 |
| AEH22754.1 | mltG | TOPB45_0652 | TOPB45_0654 | KEGG: dak:DaAHT2_1673 heat repeat-containing PBS lyase. | Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.573 |
| AEH22755.1 | AEH22753.1 | TOPB45_0653 | TOPB45_0651 | KEGG: dps:DP1095 hypothetical protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SMART: Tetratricopeptide repeat. | Tetratricopeptide TPR_1 repeat-containing protein; PFAM: Tetratricopeptide TPR-1; Tetratricopeptide TPR2; KEGG: saf:SULAZ_1707 tetratricopeptide TPR_2 repeat protein. | 0.839 |
| AEH22755.1 | AEH22754.1 | TOPB45_0653 | TOPB45_0652 | KEGG: dps:DP1095 hypothetical protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SMART: Tetratricopeptide repeat. | KEGG: dak:DaAHT2_1673 heat repeat-containing PBS lyase. | 0.839 |
| AEH22755.1 | mltG | TOPB45_0653 | TOPB45_0654 | KEGG: dps:DP1095 hypothetical protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SMART: Tetratricopeptide repeat. | Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.573 |
| argS | mltG | TOPB45_1528 | TOPB45_0654 | TIGRFAM: Arginyl-tRNA synthetase, class Ic; HAMAP: Arginyl-tRNA synthetase, class Ic; KEGG: dte:Dester_1092 arginyl-tRNA synthetase. | Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.488 |
| aroE | mltG | TOPB45_1503 | TOPB45_0654 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.616 |