Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEH22760.1PFAM: Uncharacterised conserved protein UCP033563; KEGG: ddf:DEFDS_0114 hypothetical protein. (422 aa)    
Predicted Functional Partners:
AEH22761.1
KEGG: sfu:Sfum_2771 hypothetical protein.
       0.779
AEH22763.1
PFAM: Class II aldolase/adducin, N-terminal; KEGG: mmq:MmarC5_0403 class II aldolase/adducin family protein.
       0.779
AEH22762.1
UDP-glucuronate 5'-epimerase; KEGG: pmx:PERMA_0403 NAD-dependent epimerase/dehydratase family protein; PFAM: NAD-dependent epimerase/dehydratase.
       0.777
hemL
Glutamate-1-semialdehyde 2,1-aminomutase; PFAM: Aminotransferase class-III; TIGRFAM: Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase; HAMAP: Glutamate-1-semialdehyde 2,1-aminomutase; KEGG: aar:Acear_0548 glutamate-1-semialdehyde 2,1-aminomutase.
       0.777
AEH22759.1
KEGG: pas:Pars_0947 CBS domain-containing protein; PFAM: Cystathionine beta-synthase, core; Major facilitator superfamily MFS-1; SMART: Cystathionine beta-synthase, core.
       0.507
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
Server load: low (26%) [HD]