Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH22768.1Integral membrane sensor signal transduction histidine kinase; KEGG: tye:THEYE_A1801 sensor protein AtoS; PFAM: ATP-binding region, ATPase-like; HAMP linker domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: ATP-binding region, ATPase-like; HAMP linker domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region. (473 aa)    
Predicted Functional Partners:
AEH22767.1
Two component, sigma54 specific, transcriptional regulator, Fis family; KEGG: tye:THEYE_A1802 SasR; PFAM: RNA polymerase sigma factor 54, interaction; Signal transduction response regulator, receiver region; Helix-turn-helix, Fis-type; SMART: Signal transduction response regulator, receiver region; ATPase, AAA+ type, core.
 
 
   0.853
AEH23402.1
KEGG: pbs:Plabr_1783 response regulator receiver protein; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region.
  
 
 0.774
AEH22561.1
KEGG: cch:Cag_0435 two component transcriptional regulator; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver region.
  
 
 0.734
AEH22769.1
Phosphoesterase PA-phosphatase related protein; KEGG: tye:THEYE_A1814 lipid A 1-phosphatase; PFAM: Phosphatidic acid phosphatase type 2/haloperoxidase; SMART: Phosphatidic acid phosphatase type 2/haloperoxidase.
 
  
  0.682
AEH23215.1
Hypothetical protein; KEGG: tye:THEYE_A1058 cytochrome c family protein, putative.
  
 
   0.543
AEH23406.1
Response regulator receiver protein; KEGG: dat:HRM2_37360 CheY; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region.
  
 
   0.539
AEH22766.1
KEGG: tye:THEYE_A1803 hypothetical protein.
       0.526
AEH22563.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: Diguanylate cyclase, predicted; PAS; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; KEGG: saf:SULAZ_0401 PAS fold family protein; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; PAS.
  
 
 0.486
AEH23217.1
PFAM: Cytochrome c, class III; KEGG: tye:THEYE_A1056 cytochrome c3 chain A.
  
 
  0.480
AEH23425.1
PFAM: Methyltransferase type 12; KEGG: tye:THEYE_A2047 hypothetical protein.
  
   
 0.423
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
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