| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEH22355.1 | AEH22644.1 | TOPB45_0241 | TOPB45_0542 | PFAM: Cation/H+ exchanger; Regulator of K+ conductance, N-terminal; Regulator of K+ conductance, C-terminal; KEGG: tye:THEYE_A1050 sodium/hydrogen exchanger family/TrkA domain protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | Regulatory protein MerR; SMART: HTH transcriptional regulator, MerR; KEGG: gpb:HDN1F_10630 transcriptional regulator, MerR family. | 0.504 |
| AEH22355.1 | AEH22812.1 | TOPB45_0241 | TOPB45_0710 | PFAM: Cation/H+ exchanger; Regulator of K+ conductance, N-terminal; Regulator of K+ conductance, C-terminal; KEGG: tye:THEYE_A1050 sodium/hydrogen exchanger family/TrkA domain protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | PFAM: Heavy metal transport/detoxification protein; KEGG: aae:aq_1840a copper chaperone. | 0.525 |
| AEH22355.1 | AEH22813.1 | TOPB45_0241 | TOPB45_0711 | PFAM: Cation/H+ exchanger; Regulator of K+ conductance, N-terminal; Regulator of K+ conductance, C-terminal; KEGG: tye:THEYE_A1050 sodium/hydrogen exchanger family/TrkA domain protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | TIGRFAM: ATPase, P-type, heavy metal translocating; ATPase, P type, cation/copper-transporter; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; KEGG: tna:CTN_0351 cation-transporting ATPase, P-type; PFAM: ATPase, P-type, ATPase-associated region; Heavy metal transport/detoxification protein; Haloacid dehalogenase-like hydrolase. | 0.481 |
| AEH22483.1 | AEH22644.1 | TOPB45_0377 | TOPB45_0542 | CoA-disulfide reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: dps:DP2890 NADH oxidase; SMART: Rhodanese-like. | Regulatory protein MerR; SMART: HTH transcriptional regulator, MerR; KEGG: gpb:HDN1F_10630 transcriptional regulator, MerR family. | 0.438 |
| AEH22483.1 | AEH22812.1 | TOPB45_0377 | TOPB45_0710 | CoA-disulfide reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: dps:DP2890 NADH oxidase; SMART: Rhodanese-like. | PFAM: Heavy metal transport/detoxification protein; KEGG: aae:aq_1840a copper chaperone. | 0.554 |
| AEH22483.1 | rpsP | TOPB45_0377 | TOPB45_0706 | CoA-disulfide reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: dps:DP2890 NADH oxidase; SMART: Rhodanese-like. | TIGRFAM: Ribosomal protein S16; HAMAP: Ribosomal protein S16; KEGG: cth:Cthe_0769 30S ribosomal protein S16; PFAM: Ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. | 0.403 |
| AEH22644.1 | AEH22355.1 | TOPB45_0542 | TOPB45_0241 | Regulatory protein MerR; SMART: HTH transcriptional regulator, MerR; KEGG: gpb:HDN1F_10630 transcriptional regulator, MerR family. | PFAM: Cation/H+ exchanger; Regulator of K+ conductance, N-terminal; Regulator of K+ conductance, C-terminal; KEGG: tye:THEYE_A1050 sodium/hydrogen exchanger family/TrkA domain protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | 0.504 |
| AEH22644.1 | AEH22483.1 | TOPB45_0542 | TOPB45_0377 | Regulatory protein MerR; SMART: HTH transcriptional regulator, MerR; KEGG: gpb:HDN1F_10630 transcriptional regulator, MerR family. | CoA-disulfide reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: dps:DP2890 NADH oxidase; SMART: Rhodanese-like. | 0.438 |
| AEH22644.1 | AEH22812.1 | TOPB45_0542 | TOPB45_0710 | Regulatory protein MerR; SMART: HTH transcriptional regulator, MerR; KEGG: gpb:HDN1F_10630 transcriptional regulator, MerR family. | PFAM: Heavy metal transport/detoxification protein; KEGG: aae:aq_1840a copper chaperone. | 0.502 |
| AEH22644.1 | AEH22813.1 | TOPB45_0542 | TOPB45_0711 | Regulatory protein MerR; SMART: HTH transcriptional regulator, MerR; KEGG: gpb:HDN1F_10630 transcriptional regulator, MerR family. | TIGRFAM: ATPase, P-type, heavy metal translocating; ATPase, P type, cation/copper-transporter; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; KEGG: tna:CTN_0351 cation-transporting ATPase, P-type; PFAM: ATPase, P-type, ATPase-associated region; Heavy metal transport/detoxification protein; Haloacid dehalogenase-like hydrolase. | 0.408 |
| AEH22809.1 | AEH22812.1 | TOPB45_0707 | TOPB45_0710 | HAMAP: Uncharacterised protein family UPF0109, bacterial; KEGG: dba:Dbac_3306 RNA-binding protein (KH domain); Belongs to the UPF0109 family. | PFAM: Heavy metal transport/detoxification protein; KEGG: aae:aq_1840a copper chaperone. | 0.613 |
| AEH22809.1 | AEH22813.1 | TOPB45_0707 | TOPB45_0711 | HAMAP: Uncharacterised protein family UPF0109, bacterial; KEGG: dba:Dbac_3306 RNA-binding protein (KH domain); Belongs to the UPF0109 family. | TIGRFAM: ATPase, P-type, heavy metal translocating; ATPase, P type, cation/copper-transporter; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; KEGG: tna:CTN_0351 cation-transporting ATPase, P-type; PFAM: ATPase, P-type, ATPase-associated region; Heavy metal transport/detoxification protein; Haloacid dehalogenase-like hydrolase. | 0.589 |
| AEH22809.1 | AEH22814.1 | TOPB45_0707 | TOPB45_0712 | HAMAP: Uncharacterised protein family UPF0109, bacterial; KEGG: dba:Dbac_3306 RNA-binding protein (KH domain); Belongs to the UPF0109 family. | Pyruvate carboxylase; KEGG: rca:Rcas_2955 carbamoyl-phosphate synthase L chain ATP-binding; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthase, large subunit, N-terminal; Biotin carboxylase, C-terminal. | 0.447 |
| AEH22809.1 | AEH22815.1 | TOPB45_0707 | TOPB45_0713 | HAMAP: Uncharacterised protein family UPF0109, bacterial; KEGG: dba:Dbac_3306 RNA-binding protein (KH domain); Belongs to the UPF0109 family. | Pyruvate carboxylase; KEGG: rca:Rcas_2954 biotin/lipoyl attachment domain-containing protein; PFAM: Biotin/lipoyl attachment; Conserved carboxylase region; Pyruvate carboxyltransferase. | 0.444 |
| AEH22809.1 | rimM | TOPB45_0707 | TOPB45_0708 | HAMAP: Uncharacterised protein family UPF0109, bacterial; KEGG: dba:Dbac_3306 RNA-binding protein (KH domain); Belongs to the UPF0109 family. | Ribosome maturation factor rimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. | 0.926 |
| AEH22809.1 | rpsP | TOPB45_0707 | TOPB45_0706 | HAMAP: Uncharacterised protein family UPF0109, bacterial; KEGG: dba:Dbac_3306 RNA-binding protein (KH domain); Belongs to the UPF0109 family. | TIGRFAM: Ribosomal protein S16; HAMAP: Ribosomal protein S16; KEGG: cth:Cthe_0769 30S ribosomal protein S16; PFAM: Ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. | 0.975 |
| AEH22809.1 | trmD | TOPB45_0707 | TOPB45_0709 | HAMAP: Uncharacterised protein family UPF0109, bacterial; KEGG: dba:Dbac_3306 RNA-binding protein (KH domain); Belongs to the UPF0109 family. | tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. | 0.822 |
| AEH22812.1 | AEH22355.1 | TOPB45_0710 | TOPB45_0241 | PFAM: Heavy metal transport/detoxification protein; KEGG: aae:aq_1840a copper chaperone. | PFAM: Cation/H+ exchanger; Regulator of K+ conductance, N-terminal; Regulator of K+ conductance, C-terminal; KEGG: tye:THEYE_A1050 sodium/hydrogen exchanger family/TrkA domain protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | 0.525 |
| AEH22812.1 | AEH22483.1 | TOPB45_0710 | TOPB45_0377 | PFAM: Heavy metal transport/detoxification protein; KEGG: aae:aq_1840a copper chaperone. | CoA-disulfide reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: dps:DP2890 NADH oxidase; SMART: Rhodanese-like. | 0.554 |
| AEH22812.1 | AEH22644.1 | TOPB45_0710 | TOPB45_0542 | PFAM: Heavy metal transport/detoxification protein; KEGG: aae:aq_1840a copper chaperone. | Regulatory protein MerR; SMART: HTH transcriptional regulator, MerR; KEGG: gpb:HDN1F_10630 transcriptional regulator, MerR family. | 0.502 |