Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEH22813.1TIGRFAM: ATPase, P-type, heavy metal translocating; ATPase, P type, cation/copper-transporter; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; KEGG: tna:CTN_0351 cation-transporting ATPase, P-type; PFAM: ATPase, P-type, ATPase-associated region; Heavy metal transport/detoxification protein; Haloacid dehalogenase-like hydrolase. (717 aa)    
Predicted Functional Partners:
AEH22812.1
PFAM: Heavy metal transport/detoxification protein; KEGG: aae:aq_1840a copper chaperone.
 
 
0.986
trmD
tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
       0.648
rimM
Ribosome maturation factor rimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.
  
    0.607
AEH22809.1
HAMAP: Uncharacterised protein family UPF0109, bacterial; KEGG: dba:Dbac_3306 RNA-binding protein (KH domain); Belongs to the UPF0109 family.
       0.589
AEH22814.1
Pyruvate carboxylase; KEGG: rca:Rcas_2955 carbamoyl-phosphate synthase L chain ATP-binding; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthase, large subunit, N-terminal; Biotin carboxylase, C-terminal.
     
 0.584
AEH22986.1
Regulatory protein ArsR; KEGG: tye:THEYE_A0200 heavy metal resistance transcription regulator; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR.
 
  
 0.554
AEH22815.1
Pyruvate carboxylase; KEGG: rca:Rcas_2954 biotin/lipoyl attachment domain-containing protein; PFAM: Biotin/lipoyl attachment; Conserved carboxylase region; Pyruvate carboxyltransferase.
       0.533
rpsP
TIGRFAM: Ribosomal protein S16; HAMAP: Ribosomal protein S16; KEGG: cth:Cthe_0769 30S ribosomal protein S16; PFAM: Ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
       0.524
ribBA
GTP cyclohydrolase-2; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
 0.496
AEH22355.1
PFAM: Cation/H+ exchanger; Regulator of K+ conductance, N-terminal; Regulator of K+ conductance, C-terminal; KEGG: tye:THEYE_A1050 sodium/hydrogen exchanger family/TrkA domain protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
  
  
 0.481
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.